RecruitingPhase IIEN originalLymphomaLeukemia

Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This phase II trial studies the side effects and how well combination chemotherapy and nelarabine work in treating patients with T-cell acute lymphoblastic leukemia or lymphoblastic lymphoma. Drugs used in chemotherapy, such as cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, cytarabine, mercaptopurine, prednisone, pegaspargase, nelarabine, and venetoclax work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Choroba wcześniej nie leczona lub po nieudanym pierwszym cyklu chemioterapii
  • Pacjenci w remisji po maksymalnie 2 kursach leczenia
  • Ogólny stan zdrowia pacjenta pozwala na leczenie (skala ECOG poniżej lub równa 3)
  • Prawidłowa funkcja wątroby (bilirubina do 2,0 mg/dL, bez ucisku nowotworu)

✗ Disqualifies

  • Pacjentki w ciąży lub karmiące piersią

Simplified criteria — AI translation

Trial details

Last updated (source)
July 15, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

M D Anderson Cancer Center

Houston, United States

Trial contact

Farhad Ravandi-Kashani, MD

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/16/2026.

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