Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Background: * Endocrine neoplasms (tumors) are among the fastest growing tumors in incidence in the United States. Furthermore, it is often difficult to distinguish between benign or malignant tumors in cancers of the thyroid, parathyroid, adrenal gland, and pancreas. More research is needed to improve detection and treatment options for patients who develop these kinds of cancer. * Researchers are interested in studying the molecular changes that are involved in endocrine cancer development and growth. To collect a sample of tumor specimens and healthy tissue for further study, researchers are specifically looking for samples from participants who are scheduled for surgery or biopsy on endocrine tumors. Objectives: \- To collect samples of precancerous, cancerous, and healthy tissue from individuals who are scheduled for surgery or biopsy of endocrine system tumors. Eligibility: \- Individuals who have a tumor in or around their thyroid, parathyroid, adrenal gland, pancreas, or any neuroendocrine tissue, and are scheduled for surgery at the National Institutes of Health Clinical Center. Design: * Participants in this study will provide blood and urine samples prior to surgery. * During the surgery or biopsy, pieces of the tumor or precancerous growth and pieces of normal tissue near to the tumor will be removed for ongoing and future research. The rest of the tumor or growth will be sent for analysis. * After surgery, participants will receive routine care until discharge, and doctors will discuss possible treatment options. If there is an appropriate NIH protocol, participants may choose to be treated at the NIH. * After discharge, participants will return to the clinic for a routine postoperative check about 6 weeks following the operation, and then may be followed yearly at the Clinical Center or by phone....
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Masz guza tarczycy, przytarczyc, nadnerczy, trzustki lub innego nowotworu neuroendokrynnego.
- •Masz stan przednowotworowy lub potencjalnie złośliwy, który wymaga operacji lub biopsji.
- •Masz skierowanie do poradni chorób wewnętrznych na ocenę przed operacją.
- •Twoje ogólne samopoczucie pozwala na podstawowe czynności (skala ECOG 0-2).
- •Jesteś w wieku 4 lat lub starszy/starsza.
- •Planujesz przejść operację lub biopsję guza gruczołów wydzielania wewnętrznego.
Simplified criteria — AI translation
Trial details
- Minimum age
- 4 Years
- Last updated (source)
- July 8, 2026
- Sex
- No restrictions
Locations (1)
National Institutes of Health Clinical Center
Bethesda, United States
Trial contact
Kristine J Villaruel
Naris Nilubol, M.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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