Natural History Study of Children and Adults With Medullary Thyroid Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Background: \- Medullary thyroid cancer (MTC) is a rare cancer of the thyroid gland. In children and adults, it is often part of a condition called Multiple Endocrine Neoplasia 2 (MEN2). MEN2 is usually caused by a genetic mutation, and it can cause a number of problems in addition to MTC. These problems include adrenal gland tumors, hormone changes, and problems with the bones and other organs. Not much is known about how MTC develops over time, especially in people with MEN2. Researchers want to study MTC in children and adults and see how it affects their growth and development. Objectives: \- To study how medullary thyroid cancer affects children and adults over time. Eligibility: \- Children and adults who have medullary thyroid cancer. Design: * Participants will be screened with a brief physical exam and medical history. Blood and tissue samples will be collected to see whether participants have the MEN2 genetic mutation. * Treatment will not be provided as part of this study. However, participants will be receiving standard care for MTC. They may be eligible for other clinical trials at the National Institutes of Health. * Participants will have regular study visits every 6 to 12 months to evaluate their MTC and any treatment. Blood tests, imaging studies, and other tests may be performed as needed to monitor the disease. * Participants and their parents/guardians will also complete questionnaires about their health and emotions during the study.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Dzieci i dorośli z potwierdzonym rakiem rdzeniastym tarczycy (MTC) lub potwierdzonym zespołem MEN2A lub MEN2B.
- •Pacjenci, którzy mogą podróżować do NIH i przejść badania.
- •Pacjent lub jego opiekun prawny zgadza się na udział w badaniu i podpisuje formularz świadomej zgody.
- •Włączeni są pacjenci bez wcześniejszego leczenia, z wcześniejszym leczeniem lub leczeni obecnie z powodu objawów MEN2.
- •Pacjenci muszą mieć lekarza prowadzącego, który koordynuje ich opiekę medyczną.
- •Rodzice lub główni opiekunowie pacjentów poniżej 21 roku życia z MTC lub MEN2.
- •Rodzice lub opiekunowie rozumieją i zgadzają się na udział w badaniu.
✗ Disqualifies
- •Pacjenci, którzy według lekarza nie będą mogli uczestniczyć w wizytach kontrolnych lub wymaganych badaniach.
Simplified criteria — AI translation
Trial details
- Minimum age
- 4 Months
- Last updated (source)
- July 22, 2026
- Sex
- No restrictions
Locations (1)
National Institutes of Health Clinical Center
Bethesda, United States
Trial contact
Andrea N Lucas
John W Glod, M.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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