Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Background: Urothelial cancer is cancer of the bladder, ureter, and urethra. Researchers want to better understand what changes in a person s cells and genes cause this cancer to form. This may help them find new ways to treat it. Objective: \- To perform DNA sequencing to help researchers learn the differences between normal tissue and tumor tissue. Also, to learn how molecular changes - including gene changes - might help predict the course of disease and how people respond to therapy. Eligibility: \- Adults age 18 and older who have or are suspected of having urothelial cancer or an inherited disorder that raises their risk of getting bladder cancer. Design: * Participants will be screened with a physical exam. Their medical records and tissue samples will be reviewed. * Eligible participants will give tissue blocks of their original tumor. The blocks will be put in a tissue bank. * Participants medical records may be reviewed. * Participants may have a medical history and physical exam. * Participants may have blood and urine tests. They may have imaging scans. They may give urine, blood, and saliva samples. These samples may be used in future research. * If participants need surgery for their cancer, researchers will keep some of the tissue (both tumor and normal tissue). The tissue may be used in future research. * Participants will go back to the Clinical Center in 6 months. They may give saliva, urine, and blood samples. After 6 months, they will be seen by their local doctor for standard post-surgical visits. * Participants will be called every 6 months to give health updates.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Potwierdzony lub podejrzewany rak pęcherza moczowego
- •Chęć poddania się diagnostyce lub leczeniu w ramach standardowej opieki medycznej
- •Zdolność do wyrażenia świadomej zgody na udział w badaniu
- •Zdrowi ochotnicy w wieku 18 lat lub więcej zdolni do wyrażenia zgody
✗ Disqualifies
- •Ciąża
- •Leczenie innego nowotworu (poza drobnoustrojowym rakiem skóry)
- •Historia zapalenia wątroby typu B lub C
- •Zakażenie wirusem HIV
- •Choroby serca, płuc, nerek lub inne poważne problemy zdrowotne
- •Rodzinni ochotnicy z mutacjami genetycznymi
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 120 Years
- Last updated (source)
- August 11, 2026
- Sex
- No restrictions
Locations (1)
National Institutes of Health Clinical Center
Bethesda, United States
Trial contact
Lidenys C O'Brien Gutierrez
Raju R Chelluri, M.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/12/2026.
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