RecruitingPhase IIEN originalLymphomaLeukemia

Personalized NK Cell Therapy in CBT

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with myelodysplastic syndrome, leukemia, lymphoma or multiple myeloma. This clinical trial will test cord blood (CB) selection for human leukocyte antigen (HLA)-C1/x recipients based on HLA-killer-cell immunoglobulin-like receptor (KIR) typing, and adoptive therapy with CB-derived NK cells for HLA-C2/C2 patients. Natural killer cells may kill tumor cells that remain in the body after chemotherapy treatment and lessen the risk of graft versus host disease after cord blood transplant.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Pacjenci z ostrym szpiczakiem (AML) z określonymi cechami choroby, lub po nieudanej terapii.
  • Pacjenci z zespołem mielodysplastycznym (MDS), pierwotnym lub związanym z leczeniem, z różnymi stopniami zaawansowania.
  • Pacjenci z ostrą białaczką limfoblastyczną (ALL) po niepowodzeniu terapii lub w większym niż pierwszym nawrocie, lub z wysokim ryzykiem nawrotu.
  • Pacjenci z chłoniakiem nieziarniczym (NHL) w drugim lub trzecim remisji lub nawrocie.

Simplified criteria — AI translation

Trial details

Minimum age
15 Years
Maximum age
80 Years
Last updated (source)
July 30, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

M D Anderson Cancer Center

Houston, United States

Trial contact

Warren B Fingrut, MD

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/31/2026.

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