RecruitingEN original

Clonal Evolution in Follicular Lymphoma

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

Background: Follicular lymphoma is a type of cancer of the lymph nodes. Lab studies are important for cancer research. They help scientists better understand differences in the cancer biology of different patients. Researchers want to collect serial samples over time from people with follicular lymphoma to help them design future treatments. Objective: To collect a variety of samples from people with follicular lymphoma to study how these diseases progress and respond to treatment. Eligibility: Adults at least 18 years old who have been diagnosed with, but have not yet had any treatment for, follicular lymphoma. Design: Participants will be screened with medical history and physical exam. They will answer questions about daily functioning. They will have blood and urine tests. They may have scans and have tissue samples taken. Participants will be monitored about every 4 months for up to 2 years. They will repeat screening tests. They will have a cheek swab. A small brush will be rubbed against the inside of the cheek to wipe off some cells. Participants will have imaging scans about every 8 months for up to 2 years. Participants may have a bone marrow aspiration and biopsy. The hipbone will be numbed with a small needle. A needle will be put into the hipbone, and about 2 tablespoons of bone marrow will be taken out through the needle. Participants will continue being monitored every 6 months for up to 5 years, then 1 time a year. ...

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzony diagnozą chłoniak mieszkowy (stopnie 1-2 lub 3a)
  • Wcześniejsza biopsja (pobranie tkanki) dostarczająca wystarczającą ilość materiału do badania
  • Widoczna choroba na badaniach tomograficznych (CT) lub PET
  • Wiek co najmniej 18 lat
  • Ogólny stan zdrowia pozwalający na uczestnictwo w badaniu

✗ Disqualifies

  • Wcześniejsze leczenie chemioterapią, biologiczne lub immunoterapią skierowaną na chłoniaka
  • Historia występowania innego rodzaju chłoniaka (chłoniaka rozlanego z dużych komórek B)
  • Transformacja histologiczna choroby (zmiana rodzaju chłoniaka)

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 23, 2026
Sex
No restrictions

Locations (1)

National Institutes of Health Clinical Center

Bethesda, United States

Trial contact

NCI Medical Oncology Referral Office

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/9/2026.

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