Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial studies the effect of ascorbic acid and combination chemotherapy in treating patients with lymphoma that has come back (recurrent) or does not respond to therapy (refractory), clonal cytopenia of undetermined significance and chronic myelomonocytic leukemia (CMML). Ascorbic acid may make cancer cells more sensitive to chemotherapy. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving ascorbic acid and combination chemotherapy may kill more cancer cells. Arms A, B, C, and D are closed to enrollment.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjent ma co najmniej 18 lat.
- •Potwierdzony w biopsji chłoniak, który powrócił lub nie odpowiada na leczenie.
- •Choroba jest mierzalna lub możliwa do oceny za pomocą tomografii komputerowej (CT) lub rezonansu magnetycznego (MRI). Minimalny rozmiar zmiany to 1,5 cm.
- •Pacjent kwalifikuje się do leczenia określonymi standardowymi schematami chemioterapii (w zależności od grupy badanej).
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 28, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (4)
Mayo Clinic Health Systems-Mankato
Mankato, United States
Mayo Clinic in Rochester
Rochester, United States
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, United States
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, United States
Trial contact
Clinical Trials Referral Office
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/29/2026.
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