Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The study schema is shown in Figure 4. (A) All patients referred to one of the participating academic centers for EUS evaluation of the PCL will be enrolled in the protocol if they satisfy inclusion criteria. Patient consent will be obtained during the clinic visit or prior to their EUS. EUS-guided nCLE imaging is first performed (B) followed by EUS-guided FNA and aspiration of cyst fluid. The cyst fluid is analyzed for CEA and cytology. As per institutional standard of care, the cyst fluid is also sent for molecular analysis. The results of the cyst fluid molecular analysis (B) will be utilized for the most likely diagnosis. Based on institutional multidisciplinary tumor board meetings, surgery is performed as indicated (C). Surgical histopathology serves as "gold standard" for diagnosis. It is anticipated that the majority of patients will undergo surgical resection after their EUS.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Kierowanie do badania ultrasonograficznego trzustki z powodu torbieli
- •Planowana operacja usunięcia torbieli
- •Rozmiar torbieli co najmniej 2 cm
✗ Disqualifies
- •Brak możliwości uzyskania pisemnej zgody
- •Niemożność tolerowania procedury badawczej
- •Ciąża w momencie procedury
- •Wiek poniżej 18 lat
- •Zaburzenia krzepnięcia krwi
- •Uczulenie na fluoresceínę
- •Historia raka trzustki
- •Wcześniejsza operacja trzustki
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 13, 2026
- Sex
- No restrictions
Locations (10)
Mayo Clinic Scottsdale Campus
Scottsdale, United States
Stanford Hospital
Stanford, United States
Yale School of Medicine
New Haven, United States
Parkview Hospital Randallia
Fort Wayne, United States
The Johns Hopkins Hospital
Baltimore, United States
Beth Israel Deaconess Medical Center
Boston, United States
NYU Langone Health
Garden City, United States
Icahn School of Medicine at Mount Sinai
New York, United States
The Ohio State University Wexner Medical Center
Columbus, United States
Baylor College of Medicine
Houston, United States
Trial contact
Megan Fry
Diana Burke
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/14/2026.
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