Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial studies how well venetoclax, cladribine, low dose cytarabine, and azacitidine work in treating patients with acute myeloid leukemia that has previously not been treated. Drugs used in chemotherapy, such as venetoclax, cladribine, and low dose cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Azacitidine may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving venetoclax, cladribine, low dose cytarabine induction followed by cladribine, low dose cytarabine, and azacitidine consolidation may work better in treating patients with acute myeloid leukemia.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Postawiona została nowa diagnoza białaczki ostrej szpikowej, która nie była wcześniej leczona (z małymi wyjątkami)
- •Wiek 50 lat lub więcej (młodsze osoby mogą być rozpatrzone indywidualnie)
- •Prawidłowa funkcja wątroby i nerek
- •Ogólny stan zdrowia pacjenta oceniony na 0-2 w skali ECOG
- •Test ciąży ujemny (dla kobiet w wieku rozrodczym)
✗ Disqualifies
- •Ciąża lub karmienie piersią
- •Poważne infekcje, problemy sercowe lub zaburzenia psychiczne które uniemożliwiają uczestnictwo w badaniu
- •Alergia na którykolwiek z leków w badaniu
- •Mężczyźni i kobiety w wieku rozrodczym którzy nie stosują antykoncepcji
Simplified criteria — AI translation
Trial details
- Minimum age
- 50 Years
- Last updated (source)
- October 5, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
M D Anderson Cancer Center
Houston, United States
Trial contact
Tapan Kadia
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/6/2026.
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