RecruitingPhase IIEN originalGlioma (brain cancer)

Feasibility of FMISO in Brain Tumors

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This phase II trial studies how well 18F- fluoromisonidazole (FMISO) works with positron emission tomography (PET)/magnetic resonance imaging (MRI) in assessing participants with malignant (cancerous) brain tumors. Two contrast agents called gadolinium and ferumoxytol are used during some of the MRI scans. A contrast agent is a liquid-like dye that is given intravenously (IV) to help imaging machines create pictures. The study drug, called FMISO, provides information about the oxygen levels in a tumor, which may affect how the tumor behaves. PET/MRI imaging produces images of the brain and how the body functions. FMISO PET/MRI may help investigators see how much oxygen is getting in the brain tumors.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Dorośli (18 lat i starsi) z podejrzeniem guza mózgu (glioma)
  • •Guz w mózgu większy niż 5 mL widoczny w badaniu MRI
  • •Ogólny stan zdrowia pozwalający na udział w badaniu
  • •Spodziewana długość życia co najmniej 6 miesięcy
  • •Wcześniej leczony guz mózgu lub zgoda na standardowe leczenie (operacja i chemioterapia)
  • •U kobiet zdolnych do zajścia w ciążę: ujemny test ciążowy przed badaniem
  • •Prawidłowa funkcja nerek, wątroby i innych narządów

✗ Disqualifies

  • •Ciąża lub karmienie piersią
  • •Przeciwwskazania do tomografii PET, MRI lub badanego leku FMISO
  • •Nieskontrolowana klaustrofobia
  • •Uczulenie na kontrastowe środki diagnostyczne

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 18, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

OHSU Knight Cancer Institute

Portland, United States

Trial contact

Ramon Barajas

PRINCIPAL_INVESTIGATOR

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/19/2026.

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