Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This trial studies the role of the gut microbiome and effectiveness of a fecal transplant on medication-induced gastrointestinal (GI) complications in patients with melanoma or genitourinary cancer. The gut microbiome (the bacteria and microorganisms that live in the digestive system) may affect whether or not someone develops colitis (inflammation of the intestines) during cancer treatment with immune-checkpoint inhibitor drugs. Studying samples of stool, blood, and tissue from patients with melanoma or genitourinary cancer may help doctors learn more about the effects of treatment on cells, and help doctors understand how well patients respond to treatment. Treatment with fecal transplantation may help to improve diarrhea and colitis symptoms.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Rozpoznanie czerniaka, raka płuca lub raka moczowo-płciowego
- •Leczenie lekami do kontroli punktów immunologicznych
- •Biegunka lub zapalenie jelit spowodowane lekami stosowanymi w leczeniu
- •Zdolność zrozumienia badania i chęć podpisania zgody
- •Oczekiwana długość życia powyżej 4 miesięcy
- •Ciężkie objawy biegunki lub zapalenia jelit (nie reagujące na standardowe leki)
- •Objawy nawracające po wcześniejszym leczeniu lub zależne od sterydów
✗ Disqualifies
- •Aktywna infekcja jelitowa w momencie rozpoczęcia badania
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 15, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (1)
M D Anderson Cancer Center
Houston, United States
Trial contact
Krishna Rajalu, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/16/2026.
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