RecruitingNot applicableEN originalOther cancers

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subjects. The treatment of geriatric skin with dermal rejuvenation therapies (dermabrasion, fractionated laser resurfacing) restores the appropriate UVB response. Ongoing studies have tested the ability of fractionated laser resurfacing (FLR) to assess how long this wounding effect lasts-and have found that this appears to be a durable response which lasts for at least two years. The findings that FLR protects geriatric skin at two years is the impetus for this study. This study is an interventional study to assess if FLR treatment of one forearm of geriatric subjects with multiple actinic keratosis will result in the short-term removal of actinic keratosis, and the long-term decrease in levels of future actinic keratosis and other non-melanoma skin cancers in comparison to the untreated arm. Study length and visit: The first part of the study is completed in 1 day then there are follow up visits at 90 days and every 6 months for 5 years.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 60 lat
  • Rozpoznane stwardniałe zmiany skórne w ciągu ostatnich 6 miesięcy
  • Jasna cera (typ Fitzpatrick I lub II)
  • Rozumienie procedury i związanych z nią ryzyk
  • Możliwość wyrażenia świadomej zgody
  • Posiadanie obu przedramion

✗ Disqualifies

  • Niekontrolowana cukrzyca
  • Alergia na lidokainę
  • Ciąża lub karmienie piersią
  • Historia gojenia się ze zwłóknieniami lub bliznami (w tym keloidami)
  • Choroby pogorszające się w słońcu
  • Przyjmowanie leków przeciwzapalnych (doustnych lub maści) lub sterydów
  • Duże tatuaże na przedramionach
  • Przyjmowanie leków zwiększających wrażliwość na słońce

Simplified criteria — AI translation

Trial details

Minimum age
60 Years
Last updated (source)
July 17, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Dayton VA Medical Center

Dayton, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.

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