RecruitingPhase IFemale onlyEN original

Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is single arm study of a window of opportunity in which participants with previously untreated triple negative breast cancers (TNBC) who are candidates for potentially curative surgery will receive lenvatinib 12 mg daily for 7 and pembrolizumab 200 mg IV on day 1 prior to surgery

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek co najmniej 18 lat
  • Potwierdzony histologicznie rak piersi (niedrobnokomórkowy), stadium T1b-T3, N0-N3, M0
  • Kandydat do operacyjnego leczenia radykalnego
  • Dostępna próbka tkanki z biopsji do badań
  • Planowana operacja usunięcia guza i węzłów chłonnych po chemioterapii przedoperacyjnej
  • Rak potrójnie ujemny (brak receptorów estrogenowych, progesteronowych i HER2)
  • Zadowalająca funkcja narządów wewnętrznych (wątroba, nerki, krew)
  • Brak przerzutów odległych

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
December 16, 2025
Sex
Female only

Therapies / drugs in trial

Locations (1)

University of Illinois

Chicago, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.