A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to find out whether adding pembrolizumab, with or without olaparib, to standard radiation therapy is a safe and effective treatment for metastatic breast cancer, , and to see whether the study treatment is better than, the same as, or worse than the usual approach (radiation therapy alone).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobieta w wieku co najmniej 18 lat z potwierdzonym rozpoznaniem raka piersi (typ TNBC lub ER+/HER2)
- •Ogólny stan zdrowia (ECOG) od 0 do 1 badany w ciągu 30 dni przed włączeniem do badania
- •Dla pacjentek z TNBC: wcześniejsze leczenie inhibitorami punktu kontrolnego immunologicznego z progresją choroby
- •Przystanie na udział w badaniu poprzez podpisanie świadomej zgody
- •Mierzalne zmiany chorobowe widoczne w badaniach obrazowych (co najmniej jedna zmiana pozakoślna)
- •Nie więcej niż 3 poprzednie linie leczenia układowego dla TNBC
- •Co najmniej jedno ognisko guza nadające się do radioterapii paliatywnej
- •Dostarczona próbka tkanki guza z archiwum lub nowa biopsja do badań
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- February 17, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (7)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Commack (Limited Protocol Activities)
Commack, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, United States
Trial contact
Atif Khan, MD
Simon Powell, MD
Contact information from ClinicalTrials.gov. Contact in English.
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.