99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This exploratory study conducted under the RDRC program studies the biodistribution of 99mTc-PSMA-I\&S in patients with prostate cancer who undergo pelvic lymph node dissection. Prostate specific membrane antigen (PSMA)-targeted radio-guided surgery uses the preoperative intravenous administration of a PSMA-ligand called PSMA-imaging and surgery (I\&S) labeled with the gamma-emitter radioisotope Technetium-99m (99mTc). Giving 99mTc-PSMA-I\&S may detect PSMA-expressing lymph nodes during surgery using a gamma probe and may help guide doctors to detect prostate cancer that has spread to the lymph nodes.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Mężczyźni z rakiem prostaty (zarówno nowo wykrytym, jak i nawracającym)
- •Wykonane wcześniej badanie PET/CT z użyciem znacznika PSMA-11
- •Potwierdzenie powiększonych węzłów chłonnych w badaniu PET/CT
- •Planowana operacja usunięcia węzłów chłonnych w okolicy miednicy
- •Możliwość udzielenia pisemnej i ustnej zgody na udział w badaniu
- •Możliwość wykonywania wszystkich procedur badania
✗ Disqualifies
- •Rozpoczęcie leczenia raka prostaty między włączeniem do badania a operacją
- •Węzły chłonne niedostępne do operacyjnego usunięcia
Simplified criteria — AI translation
Trial details
- Last updated (source)
- July 17, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (1)
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, United States
Trial contact
Deepu Varughese
Ankush Sachdeva
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/18/2026.
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