Pembrolizumab and Lenvatinib in Advanced Cervical Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a phase II trial of combination therapy of pembrolizumab and lenvatinib in patients with locally advanced or metastatic cervical cancer that had failed first line of therapy. The hypothesis is the combination of lenvatinib and pembrolizumab will overcome vascular endothelial growth factor (VEGF)-mediated immunosuppression to enhance the response of patients with locally advanced or metastatic cervical cancer.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobieta w wieku co najmniej 18 lat
- •Potwierdzony rozpoznaniem raka szyjki macicy (zaawansowany lub z przerzutami)
- •Choroba pogorszyła się lub była nietolerowana przy poprzednim leczeniu
- •Nie jest w ciąży i nie karmi piersią
- •Jeśli jest w wieku rozrodczym, zgadza się na antykoncepcję przez czas leczenia i 4 miesiące po
- •Ma zmienne guzy możliwe do zmierzenia w badaniach
- •Oddała próbkę tkanki guza do badania
- •Ogólny stan zdrowia na tyle dobry, że może tolerować to leczenie
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 10, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (4)
MedStar Georgetown University Hospital
Washington D.C., United States
Medstar Washington Hospital Center
Washington D.C., United States
Georgia Cancer Center at Augusta University
Augusta, United States
John Theurer Cancer Center at Hackensack UMC
Hackensack, United States
Trial contact
Jamie Magnanti
Samir Khleif, MD
PRINCIPAL_INVESTIGATOR
Emily Sarria
Sharad Ghamande, MD
PRINCIPAL_INVESTIGATOR
Oncology Clinical Research Referral Office
Donna McNamara, MD
PRINCIPAL_INVESTIGATOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/11/2026.
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