Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial studies the effect of extracorporeal photopheresis (ECP) and mogamulizumab in treating patients with erythrodermic cutaneous T cell lymphoma (CTCL), a type of skin lymphoma. CTCL is a rare type of cancer that begins in the white blood cells called T cells. Erythrodermic is a widespread red rash that may cover most of the body. ECP is a medical treatment that removes blood with a machine, isolates white blood cells and exposes them to ultra violet light, then returns the cells to the body. Mogamulizumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Giving mogamulizumab with ECP may work together to kill the tumor cells directly (with mogamulizumab) and boost immune response to cancer (with ECP).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Rozpoznanie potwierdzonym biopsją: grzybica włosów lub zespół Sezary'ego
- •Zaawansowany stadion choroby (od stadium IB)
- •Mierzalne objawy choroby widoczne w badaniu skóry lub test komórek Sezary'ego
- •Próbka skóry pobrana w ciągu ostatnich 6 miesięcy dostępna do oceny
- •Wystarczająca liczba neutrofili we krwi (bez zajęcia szpiku kostnego)
- •Zgodę na użycie archiwum tkanek z biopsji diagnostycznej
- •Zdolność do uczestnictwa w badaniu (stan ogólny pacjenta ECOG ≤ 2)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 2, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (3)
Mayo Clinic
Scottsdale, United States
City of Hope Medical Center
Duarte, United States
Winship Cancer Institute of Emory University
Atlanta, United States
Trial contact
Christiane R. Querfeld
Christiane R. Querfeld
PRINCIPAL_INVESTIGATOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/3/2026.
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