RecruitingEN originalColorectal cancer

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study measures the levels of circulating tumor DNA (ctDNA) in patients with stage II-III rectal cancer before, during, and after treatment to find out if the presence or absence of ctDNA in patient's blood using the Signatera test can be used to gauge how different treatments may affect rectal cancer. ctDNA is DNA from the rectal cancer that is circulating in the blood. The purpose of this study is to understand if the way rectal tumors respond to standard treatment can be associated with varying levels of ctDNA.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek co najmniej 18 lat
  • •Potwierdzony patologicznie rak gruczołowy odbytnicy II lub III stopnia zaawansowania
  • •Pisemna zgoda na uczestnictwo w badaniu

✗ Disqualifies

  • •Przerzuty nowotworu do odległych miejsc w organizmie
  • •Wcześniejsze leczenie raka odbytnicy
  • •Transfuzja krwi w ciągu ostatniego miesiąca

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 16, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (2)

OHSU Knight Cancer Institute

Portland, United States

Fred Hutch

Seattle, United States

Trial contact

Adel Kardosh, M.D.,Ph.D.

Adel Kardosh, M.D.,Ph.D.

PRINCIPAL_INVESTIGATOR

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/17/2026.

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