A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
In phase Ia study, the safety and tolerability of BL-B01D1 in patients with locally advanced or metastatic solid tumor will be investigated to determine the dose-limiting toxicity (DLT), maximum tolerated dose (MTD) of BL-B01D1. In phase Ib study, the safety and tolerability of BL-B01D1 at the phase Ia recommended dose will be further investigated, and recommended phase II dose (RP2D) for phase II clinical studies will be determined. In addition, the preliminary efficacy, pharmacokinetic characteristics, and immunogenicity of BL-B01D1 in patients with locally advanced or metastatic solid tumor will be evaluated.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek od 18 do 75 lat (faza Ia) lub od 18 lat wzwyż (faza Ib)
- •Potwierdzony zaawansowany lub przerzutowy nowotwór, który nie poddaje się leczeniu standardowemu
- •Spodziewany czas przeżycia co najmniej 3 miesiące
- •Ogólny stan zdrowia pozwalający na udział w badaniu (aktywność do 1 stopnia)
- •Poprzednie leczenie nowotworów ustąpiło (nie ma poważnych skutków ubocznych)
- •Prawidłowe działanie serca (wyrzutność lewej komory minimum 50%)
- •Prawidłowe wyniki badań krwi i pracy nerek
- •Gotowość do dostarczenia próbki guza lub zgoda na jej pobranie
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 75 Years
- Last updated (source)
- August 27, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (8)
Chongqing University Cancer Hospital
Chongqing, China
Sun Yat-sen University Cancer Center
Guangzhou, China
The Second Affiliated Hospital of Guangzhou Medical University
Guangzhou, China
Renmin Hospital of Wuhan University
Wuhan, China
Union Hospital Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China
Hunan Cancer Hospital
Changsha, China
Shanghai Oriental Hospital
Shanghai, China
Shanxi Cancer Hospital
Taiyuan, China
Trial contact
Sa Xiao, PHD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/28/2026.
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