A Study Comparing Perioperative Stress Reduction vs. Standard of Care in Ovarian Cancer (PRESERVE)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The purpose of this study is to see if propranolol and etodolac along with mind-body resilience training/MBRT and music therapy help participants who are experiencing physiological stress before, during, and after primary debulking surgery/PDS or IDS and also if it's better than the standard-of-care approach (no intervention for reducing stress).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjentki z zaawansowanym rakiem jajnika, jajowodu lub otrzewnej (stadium II-IV).
- •Zaplanowana operacja mająca na celu usunięcie guza (PDS lub IDS).
- •Wiek 18 lat lub więcej.
- •Ogólnie dobry stan zdrowia pozwalający na operację (oceniany przez lekarza).
✗ Disqualifies
- •Przyjmowanie na stałe leków z grupy beta-blokerów lub COX inhibitorów.
- •Choroby uniemożliwiające stosowanie beta-blokerów (np. astma, problemy z sercem).
- •Choroby uniemożliwiające stosowanie COX inhibitorów (np. niewydolność nerek, choroby wątroby, choroba wrzodowa).
- •Ciąża lub planowanie ciąży.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 1, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (7)
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, United States
Memorial Sloan Kettering Monmouth (Limited protocol activities)
Middletown, United States
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, United States
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited protocol activities)
Commack, United States
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, United States
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, United States
Trial contact
Kara Long Roche, MD
Anoushka Afonso, MD
Contact information from ClinicalTrials.gov. Contact in English.
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.