Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
It is currently unclear if immediate curative treatment (radiotherapy or surgery) of high-risk prostate cancer without metastasis in older men (\>=75 years) generates the same survival benefits as in younger patients or if the harms/ side-effects of immediate curative treatment outweigh the benefits. In this study the investigators randomize older patients with high-risk, non-metastatic high-risk prostate cancer to either immediate curative therapy or to conservative, more problem-oriented therapy to investigate if immediate curative treatment prolongs life, improves quality of life and is cost-effective.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 75 lat
- •Dobry stan zdrowia potwierdzone badaniem lekarskim i testami do oceny sprawności
- •Rak prostaty rozpoznany nie więcej niż 6 miesięcy temu, z wysokim stopniem zaawansowania
- •Mężczyzna
- •Zdolność do podpisania zgody na udział w badaniu
- •Zdolność do wypełniania kwestionariuszy dotyczących jakości życia
✗ Disqualifies
- •Demencja lub zaburzenia pamięci uniemożliwiające wyrażenie świadomej zgody
- •Wcześniejsza radioterapia miednicy
- •Hormonterapia przez więcej niż 3 miesiące przed badaniem
- •Przerzuty do węzłów chłonnych lub odległe przerzuty
- •Poważne problemy zdrowotne lub znaczne ograniczenia funkcjonalne
- •Niezdolność do wypełniania kwestionariuszy dotyczących jakości życia
Simplified criteria — AI translation
Trial details
- Minimum age
- 75 Years
- Last updated (source)
- September 10, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (26)
Rigshospital
Copenhagen, Denmark
Esbjerg and Grindsted Hospital
Esbjerg, Denmark
Odense University Hospital
Odense, Denmark
Helsinki University Hospital
Helsinki, Finland
Tampere University Hospital
Tampere, Finland
Turku University Hospital
Turku, Finland
Sunmøre Hospital Trust
Ålesund, Norway
Stavanger University Hospital
Stavanger, Norway
Sørlandet Hospital Trust
Kristiansand, Norway
Telemark Hospital Trust
Skien, Norway
St. Olavs Hospital
Trondheim, Norway
Vestfold Hospital Trust (Hospital of Vestfold)
Tønsberg, Norway
Vestre Viken Hospital Trust
Drammen, Norway
Innlandet Hospital Trust
Hamar, Norway
Akerhus University Hospital
Lørenskog, Norway
Oslo University Hospital
Oslo, Norway
University Hospital of Northern Norway
Tromsø, Norway
Falu Lasarett
Falun, Sweden
Sahlgrenska University Hospital
Gothenburg, Sweden
Helsingborg/Ängelholm hospital
Helsingborg, Sweden
Örebro University Hospital
Örebro, Sweden
Östersunds Hospital
Östersund, Sweden
Capio Saint Göran's Hospital
Stockholm, Sweden
Södersjukhuset
Stockholm, Sweden
Norrlands universitetssjukhus
Umeå, Sweden
Akademiska sjukhuset, Uppsala
Uppsala, Sweden
Trial contact
Sven Loffeler, MD, PhD
Erik S Haug, MD, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/11/2026.
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