RecruitingEarly Phase IMale onlyEN originalProstate cancerEarly / localized

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This study will establish the preferred dose of lisinopril in men with non-metastatic prostate cancer undergoing radiation treatment. This study will also evaluate the effect of lisinopril on urinary symptoms and the impact of lisinopril on biomarkers and their association with urinary symptoms.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Potwierdzony diagnoza raka prostaty kwalifikujący się do radioterapii
  • Rak bez przerzutów (stadium M0)
  • Wiek od 18 do poniżej 70 lat
  • Dobry stan ogólny pozwalający na uczestnictwo w badaniu
  • Prawidłowa funkcja nerek (wynik testu kreatyniny większy niż 30)
  • Prawidłowe wyniki badań krwi (hemoglobina minimum 9,0, płytki krwi minimum 100 000)
  • Ciśnienie skurczowe powyżej 130 mmHg
  • Znajomość języka angielskiego

✗ Disqualifies

  • Poprzednia radioterapia miednicy
  • Przyjmowanie leku lisinopril lub podobnych leków w ciągu ostatnich 2 miesięcy
  • Alergia na lisinopril

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
70 Years
Last updated (source)
July 23, 2026
Sex
Male only

Therapies / drugs in trial

Locations (1)

Wilmot Cancer Institute

Rochester, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/24/2026.

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