Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Background: Myelodysplastic syndromes (MDS) are disorders of blood stem cells that can develop into blood cancers. Treatment options are limited. To find better treatments, researchers need to better understand how MDS develops. To do that, they must be able to compare biospecimens from people with the disease to those of healthy people. Objective: This study will create a database of biospecimens collected from healthy volunteers. Eligibility: Healthy people aged 18 and older. Design: Participants will be screened. They will have a physical exam with blood and urine tests. Up to 5 types of samples will be collected on 1 or more days within 1 month of screening: Blood: Blood will be drawn by inserting a needle into a vein. Saliva: Participants will scrape the insides of their cheeks with a brush. Stool: Participants will be given a container to collect stool at home. They will use a prepaid envelope to mail in the sample. Bone marrow: A sample of the soft tissue inside the bones will be drawn out. The area to be biopsied, usually the lower back, will be numbed. A needle will be inserted through a small cut to remove the sample. Participants' pain will be monitored; additional numbing medicine may be used. Skin: A piece of skin about 1/6 of an inch across will be cut away. Stitches may be used to close the wound. Participants will return to the clinic to have the stitches removed. Participants do not have to provide all of the samples listed. They will give each sample only once.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Osoby w wieku 18 lat i starsze.
- •Osoby zdrowe, co zostanie potwierdzone przez lekarza na podstawie wywiadu, badania i wyników badań krwi.
- •Osoby rozumiejące cel badania i zgadzające się na udział.
- •Wyniki badań krwi muszą mieścić się w normie dla wieku i stanu zdrowia.
✗ Disqualifies
- •Aktywne choroby, obniżona odporność, choroby autoimmunologiczne, choroby nowotworowe (obecne lub w przeszłości).
- •Przeszczep narządu, szpiku kostnego lub komórek krwiotwórczych w ciągu ostatnich 3 miesięcy.
- •Przyjmowanie leków osłabiających odporność.
- •Objawy takie jak biegunka, zaparcie, wzdęcia lub ból brzucha w ciągu ostatnich 3 miesięcy.
- •Historia zakażenia wirusem HIV, zapalenia wątroby typu C (HCV) lub B (HBV).
- •Kobiety w ciąży lub karmiące piersią.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Maximum age
- 120 Years
- Last updated (source)
- July 23, 2026
- Sex
- No restrictions
Locations (1)
National Institutes of Health Clinical Center
Bethesda, United States
Trial contact
Danielle F Pinkiert, R.N.
Kathy L McGraw, Ph.D.
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.
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