RecruitingPhase IIEN originalGlioma (brain cancer)

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a Phase 2, randomized two-armed, multi-site study of 170 patients with newly diagnosed glioblastoma multiforme. Patients will be randomized 1:1 to receive Keto Diet, or Standard Anti-Cancer Diet. All patients will receive standard of care treatment for their glioblastoma. The Keto Diet intervention will be for an 18-week period and conducted by trained research dietitians. Daily ketone and glucose levels will be recorded to monitor Keto Diet adherence. This two-armed randomized multi-site study aims to provide evidence to support the hypothesis that a Keto Diet vs. Standard Anti-Cancer Diet improves overall survival in newly diagnosed glioblastoma multiforme patients who receive standard of care treatment.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek 18 lat lub więcej
  • Nowo rozpoznany glejiak mózgu (w ciągu 2 miesięcy od diagnozy)
  • Nie rozpoczęta chemioterapia ani radioterapia
  • Ogólny stan zdrowia pozwalający na udział w badaniu (KPS ≥ 70)
  • Możliwość czytania i rozumienia instrukcji w języku angielskim lub hiszpańskim
  • Świadoma zgoda na udział w badaniu

✗ Disqualifies

  • Glejiak nawracający (powrót nowotworu)
  • Zaburzenia metabolizmu tłuszczów
  • Niemożność zmniejszenia dawki sterydów poniżej 8 mg dziennie
  • Wskaźnik masy ciała poniżej 21 kg/m²
  • Ciąża lub karmienie piersią
  • Uczestnictwo w innym eksperymentalnym leczeniu
  • Urządzenia medyczne incompatybilne z rezonansem magnetycznym (rozrusznik serca, implanty)
  • Preferencje żywieniowe niezgodne z dietą ketogeniczną

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 5, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (5)

Cedars-Sinai Medical Center

Los Angeles, United States

University of California, San Francisco

San Francisco, United States

Pacific Neuroscience Institute / Saint John's Cancer Institute

Santa Monica, United States

Duke University

Durham, United States

Medical College of Wisconsin

Milwaukee, United States

Trial contact

Clinical Trial Recruitment Navigator

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/6/2026.

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