Early Detection and Screening of Hematological Malignancies - SANGUINE
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a multicenter, open-label, non-interventional controlled study to identify and characterize the epigenetic signatures for a set of hematological malignancies: Multiple myeloma (MM), pre-MM conditions \[smoldering MM (SMM) and monoclonal gammopathy of undetermined significance (MGUS)\], Hodgkin lymphoma (HL), diffuse large B cell lymphoma (DLBCL), Follicular lymphoma (FL), Marginal Zone lymphomas (MZL), acute myeloid leukemia (AML)\*, myelodysplastic syndrome (MDS), subjects at risk and control subjects with no malignant disease. \*Patients with a diagnosis of acute promyelocytic leukemia (APL) are not included
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Umiejętność zrozumienia i chęć podpisania świadomej zgody
- •Rozpoznanie jednego z badanych nowotworów krwi (przed rozpoczęciem leczenia lub podczas obserwacji)
- •Dla osób z grupy ryzyka: krewny pierwszego stopnia lub wiek co najmniej 65 lat
✗ Disqualifies
- •Inny rodzaj raka zdiagnozowany równocześnie
- •Rak rozpoznany w ciągu ostatnich 2 lat (z wyjątkiem raka skóry)
- •Rozpoznanie białaczki promielocytowej
- •Aktywna choroba autoimmunologiczna wymagająca leczenia
- •Zakażenie wirusem HIV
- •Aktywne zapalenie wątroby typu A, B lub C
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 15, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (4)
Fakultni Nemocnice Olomouc (Fnol)
Olomouc, Czechia
National and Kapodistrian University of Athens (NKUA)
Athens, Greece
Tel-Aviv Sourasky Medical Center (TASMC)
Tel Aviv, Israel
Vilnus University Hospital Santaros Klinikos (VULSK)
Vilnius, Lithuania
Trial contact
Helena Grinberg-Rashi, PhD
Yael Michaeli, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/16/2026.
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