RecruitingEN originalLeukemia

Determining the Mechanisms of Loss of CAR T Cell Persistence

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

A prospective observational study of pediatric and young adult acute lymphoblastic leukaemia (ALL) patients treated with CD19 chimeric antigen receptor T-cells (CAR-T cells). The study will examine changes in CAR-T persistence over time and causal factors.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Dzieci i młodzi dorośli (do 25 lat) z białaczką limfoblastyczną, która powróciła lub nie poddaje się leczeniu
  • Pacjenci zaplanowani do leczenia zatwierdzonymi komórkami CAR-T skierowanymi na CD19
  • Pisemna zgoda rodzica lub opiekuna na uczestnictwo w badaniu

✗ Disqualifies

  • Pacjenci już uczestniczący w innym badaniu klinicznym z innymi komórkami CAR-T
  • Osoby, które mogą mieć trudności z realizacją wymogów badania

Simplified criteria — AI translation

Trial details

Maximum age
25 Years
Last updated (source)
August 7, 2026
Sex
No restrictions

Locations (3)

Great Ormond Street Hospital

London, United Kingdom

University College London Hospital

London, United Kingdom

Royal Manchester Children's Hospital

Manchester, United Kingdom

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/8/2026.

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