Targeted Pediatric High-Grade Glioma Therapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this study is to perform genetic sequencing on brain tumors from children, adolescents, and young adult patients who have been newly diagnosed with a high-grade glioma. This molecular profiling will decide if patients are eligible to participate in a subsequent treatment-based clinical trial based on the genetic alterations identified in their tumor.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek pacjenta: od 12 miesięcy do 39 lat w momencie włączenia do badania
- •Świeżo zdiagnozowany glejak wysokiego stopnia złośliwości potwierdzony biopsją lub operacją
- •Brak wymagań dotyczących zaawansowania choroby - pacjenci z przerzutami i chorobą rozproszoną mogą uczestniczyć
- •Możliwość poddania się operacji, radioterapii lub leczenia dexametazonem przed badaniem
- •Dostępna próbka guza do badania genetycznego lub wyniki wcześniejszych badań genetycznych
✗ Disqualifies
- •Radioterapia przed badaniem (dla grupy TarGeT-L)
- •Zastosowanie innych leków przeciwnowotworowych poza wymienionymi dozwolonymi
Simplified criteria — AI translation
Trial details
- Minimum age
- 12 Months
- Maximum age
- 39 Years
- Last updated (source)
- September 8, 2026
- Sex
- No restrictions
Locations (22)
Children's Hospital Colorado
Aurora, United States
Children's National Medical Center
Washington D.C., United States
University of Miami
Miami, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
Dana-Farber Cancer Institute
Boston, United States
C.S. Mott Children's Hospital
Ann Arbor, United States
Duke University Health System
Durham, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Nationwide Children's Hospital
Columbus, United States
Children's Hospital of Philadelphia
Philadelphia, United States
Texas Children's Hospital
Houston, United States
Seattle Children's Hospital
Seattle, United States
Sydney Children's Hospital
Randwick, Australia
Queensland Children's Hospital
South Brisbane, Australia
Royal Children's Hospital
Melbourne, Australia
Perth Children's Hospital
Perth, Australia
The Hospital for Sick Children (SickKids)
Toronto, Canada
Montreal Children's Hospital
Montreal, Canada
Hopp Children's Cancer Center at NCT Heidelberg (KiTZ)
Heidelberg, Germany
Princess Máxima Center
Utrecht, Netherlands
Starship Children's Hospital
Auckland, New Zealand
Great Ormond Street Hospital
London, United Kingdom
Trial contact
Kelsey H Troyer, PhD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/9/2026.
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