Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

Functional precision medicine (FPM) is a relatively new approach to cancer therapy based on direct exposure of patient- isolated tumor cells to clinically approved drugs and integrates ex vivo drug sensitivity testing (DST) and genomic profiling to determine the optimal individualized therapy for cancer patients. In this study, we will enroll relapsed or refractory pediatric cancer patients with tissue available for DST and genomic profiling from the South Florida area, which is 69% Hispanic and 18% Black. Tumor cells collected from tissue taken during routine biopsy or surgery will be tested.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek do 21 lat w momencie włączenia do badania
  • Podejrzenie lub potwierdzenie nawrotowego albo opornego na leczenie nowotworu
  • Niedawno przebyta biopsja lub usunięcie guza
  • Chęć oddania próbki krwi lub wymazru ze śluzówki policzka do badań genetycznych
  • Wyrażona zgoda pacjenta, rodziców lub opiekunów
  • Dzieci w wieku 7-17 lat mogą podpisać zgodę na uczestnictwo

✗ Disqualifies

  • Brak dostępu do tkanki nowotworowej do badania
  • Zbyt mała ilość tkanki do przeprowadzenia testów
  • Świeżo wykryty nowotwór, który ma duże szanse na wyleczenie standardowym leczeniem

Simplified criteria — AI translation

Trial details

Minimum age
1 Day
Maximum age
21 Years
Last updated (source)
August 26, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Nicklaus Children's Hospital

Miami, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/27/2026.

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