RecruitingPhase IIIFemale onlyEN originalBreast cancerTriple negative (TNBC)Early / localized

A Multi-center, Randomized, Open-label, Phase III Study Comparing PD-1 Inhibitor Combined With Antivascular Therapy and Anthracycline/Taxane-based Adjuvant Chemotherapy Versus Anthracycline/Taxane-based Adjuvant Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This review will evaluate the efficacy and safety of SHR1210 (Camrelizumab) and antivascular drug(Famitinib) in combination with anthracyclines/taxane-based adjuvant chemotherapy (carrelizumab + FAM + EC-P) compared with conventional chemotherapy regimens (dose-intensive epirubicin and cyclophosphamide, sequential paclitaxel, or EC-P) in patients with early-stage high-risk TNBC.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Podpisanie świadomej zgody na uczestnictwo w badaniu
  • Wiek 18-70 lat w momencie podpisania zgody
  • Dobry stan ogólny zdrowia (ocena ECOG: 0 lub 1)
  • Rak piersi triple-negative w stadium IIA-IIIIC, bez przerzutów, po zabiegu chirurgicznym
  • Potwierdzenie w badaniu histologicznym: ujemne markery HER2, receptorów estrogenowych i progesteronowych
  • Wykonanie zabiegu: oszczędzającego pierś lub całkowitego usunięcia piersi
  • Prawidłowe wyniki badań laboratoryjnych (liczba krwinek, wątroby i nerek) z ostatnich 28 dni
  • Dla kobiet w wieku rozrodczym: stosowanie antykoncepcji przez co najmniej 5 miesięcy po zakończeniu leczenia

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
70 Years
Last updated (source)
July 16, 2025
Sex
Female only

Therapies / drugs in trial

Locations (1)

Breast cancer institute of Fudan University Cancer Hospital

Shanghai, China

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

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