Study of AVZO-021 in Patients With Advanced Solid Tumors
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This study, the first clinical trial of AVZO-021, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and anti-tumor effects of AVZO-021 in patients with advanced solid tumors. AVZO-021 is an oral medication that inhibits cyclin-dependent kinase 2 (CDK 2).
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek minimum 18 lat, w dobrym ogólnym stanie zdrowia (skala ECOG 0-1)
- •Rak piersi zaawansowany lub przerzutowy z określonymi cechami genetycznymi, który nie reaguje na standardowe leczenie
- •Raki jajników, otrzewnej lub jajnika maluszkowego z amplifikacją genu CCNE1, które nie reagują na standardowe leczenie
- •Rak piersi, który wcześniej był leczony inhibitorami CDK4/6 i hormonoterapią
- •Raki jajnika oporne na chemioterapię platynową, które nie reagują na standardowe leczenie
- •Możliwość zmierzenia rozmiaru nowotworu za pomocą badań obrazowych (RECIST 1.1)
- •Prawidłowa funkcja szpiku kostnego i narządów wewnętrznych
- •Zdolność do połykania tabletek lub kapsułek
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- September 28, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (13)
Avenzo Therapeutics Recruiting Site
New Haven, United States
Avenzo Therapeutics Recruiting Site
Sarasota, United States
Avenzo Therapeutics Recruiting Site
Tampa, United States
Avenzo Therapeutics Recruiting Site
Mineola, United States
Avenzo Therapeutics Recruiting Site
New York, United States
Avenzo Therapeutics Recruiting Site
Cleveland, United States
Avenzo Therapeutics Recruiting Site
Oklahoma City, United States
Avenzo Therapeutics Recruiting Site
Portland, United States
Avenzo Therapeutics Recruiting Site
Philadelphia, United States
Avenzo Therapeutics Recruiting Site
Dallas, United States
Avenzo Therapeutics Recruiting Site
Fairfax, United States
Avenzo Therapeutics Recruiting Site
Macquarie University, Australia
Avenzo Therapeutics Recruiting Site
Wollongong, Australia
Trial contact
Medical Information
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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