WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial tests how well the combination of WP1066 and radiation therapy works in treating newly diagnosed glioblastoma. Glioblastoma is difficult to treat effectively because the cells within the tumor vary widely and are controlled by factors within and around the tumor, requiring multiple approaches to treat the tumor. The study drug WP1066 targets a specific pathway, known as STAT3, which is responsible for promoting tumor growth and causing the body's immune system to avoid attacking the tumor. Radiation therapy prevents glioblastoma from growing. Giving WP1066 with radiation therapy may prevent glioblastoma from growing and prolong survival.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Świeżo rozpoznany glejak potwierdzony histologicznie (typ IDH wild-type)
- •Badanie genetyczne IDH wykazujące status wild-type
- •Badanie MGMT wykazujące status niezmutowany
- •Wiek co najmniej 18 lat
- •Ogólny stan zdrowia na poziomie co najmniej 60% w skali Karnofskiego
- •Wystarczająca liczba białych krwinek (≥3,0)
- •Wystarczająca liczba płytek krwi (≥75)
- •Rozpoczęcie leczenia w ciągu 8 tygodni od operacji diagnostycznej mózgu
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 22, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (2)
Northwestern University
Chicago, United States
Northwestern Medicine: Warrenville
Warrenville, United States
Trial contact
Amy Heimberger
Amy Heimberger
PRINCIPAL_INVESTIGATOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/23/2026.
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