Efficacy and Safety of Frontline Tislelizumab in Patients With de Novo Hodgkin Lymphoma Unsuitable for Standard Frontline Chemotherapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a multicenter, prospective, non-randomized, open-label, phase 2 clinical study to evaluate the efficacy and safety of tislelizumab in patients with de novo Hodgkin Lymphoma deemed ineligible to frontline chemotherapy.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony histologicznie (badaniem mikroskopowym) klasyczny chłoniak Hodgkina
- •Wiek 65 lat lub więcej i niemożliwość otrzymywania standardowej chemioterapii ze względu na problemy zdrowotne
- •Wcześniej niezleczony z tego schorzenia
- •Mierzalne ogniska choroby widoczne w badaniach obrazowych
- •Oczekiwanie na systemowe leczenie przeciwnowotworowe
- •Dobry stan ogólny pacjenta (skala ECOG ≤ 2)
- •Prawidłowa funkcja nerek, wątroby i szpiku kostnego
- •Oczekiwana długość życia co najmniej 6 miesięcy
Simplified criteria — AI translation
Trial details
- Minimum age
- 65 Years
- Last updated (source)
- August 19, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (12)
A.O. SS. Antonio e Biagio e Cesare Arrigo, S.C. Ematologia
Alessandria, Italy
Divisione di Oncologia e dei Tumori immuto-correlati, Centro Di Riferimento Oncologico Di Aviano
Aviano, Italy
Istituto di Ematologia L. e A. Seràgnoli, AOU Policlinico S. Orsola-Malpighi
Bologna, Italy
SC Ematologia, Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Brescia, Italy
Ematologia, Fondazione IRCCS Istituto Nazionale Dei Tumori
Milan, Italy
Unità di Ematologia e TMO - Unità Linfomi, Ospedale San Raffaele
Milan, Italy
Oncologia, IRCCS Istituto Nazionale Tumori Fondazione Pascale
Naples, Italy
SCDU Ematologia - AOU Maggiore della Caritа di Novara
Novara, Italy
Oncoematologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello
Palermo, Italy
Ematologia - Azienda Unitа Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova
Reggio Emilia, Italy
Istituto Ematologia -Dipartimento di Medicina Traslazionale e di Precisione, Azienda Ospealiero Universitaria Policlinico Umberto I
Roma, Italy
U.O di Oncologia Medica ed Ematologia, Humanitas Research Hospital
Rozzano, Italy
Trial contact
Uffici Studi FIL
Uffici Studi FIL
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/20/2026.
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