Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This clinical trial compares the effectiveness of geriatric assessment (GA) guided interventions to accelerate functional recovery after chimeric antigen receptor T-cell (CAR-T) therapy compared to standard of care (SOC) in patients 60 years and older with B-cell non-Hodgkin lymphoma (NHL) or multiple myeloma (MM). A large number of patients diagnosed with cancer are over the age of 60, yet most cancer treatments are developed for younger patients. Therefore, older patients may be less likely to be offered stronger treatments, such as CAR-T therapy, due to possible side effects. Geriatric assessment is a multi-dimensional health assessment tool combining patient reported and objective measures covering physical function, mental processes (cognitive), and nutrition. Pre-treatment assessments may identify weaknesses in older adults and may guide interventions for physical therapy, cognitive changes and nutrition to decrease CAR-T therapy side effects and improve care in older adults with NHL or MM.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjent wyraża zgodę na udział.
- •Lekarz prowadzący pacjenta zgadza się na jego udział w badaniu.
- •Pacjent potrafi czytać po angielsku lub hiszpańsku (inne języki możliwe za zgodą).
- •Pacjent ma 60 lat lub więcej.
- •Pacjent ma otrzymać zatwierdzoną przez FDA terapię CAR-T na chłoniaka nieziarniczego lub szpiczaka mnogiego.
- •Pacjent chce i może wypełnić wymagania badania.
- •Pacjent spodziewa się móc uczestniczyć w wizytach przed leczeniem.
✗ Disqualifies
- •Pacjent wcześniej otrzymywał terapię CAR-T.
- •Stan zdrowia pacjenta, według oceny lekarza, może być przeciwwskazaniem do udziału w badaniu ze względów bezpieczeństwa.
- •Pacjent, według oceny lekarza, może nie być w stanie stosować się do wszystkich procedur badawczych.
Simplified criteria — AI translation
Trial details
- Minimum age
- 60 Years
- Last updated (source)
- September 25, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (4)
City of Hope Medical Center
Duarte, United States
City of Hope at Irvine Lennar
Irvine, United States
Wake Forest University, School of Medicine Dept. of Internal Medicine, Division of Hematology Oncology
Winston-Salem, United States
Ohio State University Medical Center Dept. of Internal Medicine, Division of Hematology
Columbus, United States
Trial contact
Andrew S. Artz
Andrew S. Artz
PRINCIPAL_INVESTIGATOR
Andrew Artz, MD
Heidi Klepin, MD
Ashley Rosko, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/26/2026.
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