A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

Southern Cancer Center

Daphne, United States

Sutter Auburn Faith Hospital

Auburn, United States

La Hematology Oncology Medical Group

Glendale, United States

Marin Cancer Care Inc

Greenbrae, United States

Kaiser Permanente - Harbor City

Harbor City, United States

USC Norris Comprehensive Cancer Center

Los Angeles, United States

USC Norris Cancer Center

Newport Beach, United States

Sutter Medical Group, Roseville Clinic

Roseville, United States

Sutter Health Medical Center

Sacramento, United States

The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Cente

Torrance, United States

Rocky Mountain Cancer Centers

Littleton, United States

Georgetown University Medical Center

Washington D.C., United States

MedStar Washington Hosp Center

Washington D.C., United States

AdventHealth Altamonte

Altamonte Springs, United States

Florida Cancer Specialists - Broadway

Fort Myers, United States

Cancer Specialists of North Florida

Jacksonville, United States

Florida Cancer Specialists - North;725 6th Ave South (St. Petersburg)

St. Petersburg, United States

Comprehensive Hematology Oncology

St. Petersburg, United States

Florida Cancer Specialists - EAST - SCRI - PPDS

West Palm Beach, United States

Grady Health System

Atlanta, United States

Winship Cancer Institute of Emory University

Atlanta, United States

Advocate Lutheran General Hospital

Park Ridge, United States

Springfield Clinic

Springfield, United States

Mission Cancer + Blood - IMMC

Des Moines, United States

Baptist Health Lexington

Lexington, United States

Baptist Health Hamburg

Lexington, United States

Baptist Health Louisville

Louisville, United States

New England Cancer Specialists

Scarborough, United States

Maryland Oncology Hematology

Annapolis, United States

Frederick Health Hospital

Frederick, United States

Dana Farber Cancer Institute

Boston, United States

Henry Ford Hospital

Detroit, United States

HCA Midwest Division

Kansas City, United States

Cancer Care Center of O'Fallon

O'Fallon, United States

Oncology Hematology West - Grand Island

Grand Island, United States

Oncology Hematology West - Legacy

Omaha, United States

Astera Cancer Care East Brunswick

East Brunswick, United States

Capital Health Regional Medical Center

Pennington, United States

Queens Hospital Cancer Center

Jamaica, United States

Duke Women Cancer Care

Raleigh, United States

Oncology Hematology Care

Cincinnati, United States

Asante Rogue Regional Medical Center

Medford, United States

Alliance Cancer Specialists

Bensalem, United States

Ann B. Barshinger Cancer Institute

Lancaster, United States

Abramson Cancer Center; Univ of Pennsylvania; Clinical Research Unit

Philadelphia, United States

WellSpan Oncology Research

York, United States

Brown University Health

Providence, United States

Medical University of South Carolina

Charleston, United States

Avera Cancer Institute - Aberdeen

Aberdeen, United States

Avera Cancer Institute

Sioux Falls, United States

West Cancer Center

Germantown, United States

SCRI Oncology Partners

Nashville, United States

Texas Oncology Cancer Center

Austin, United States

JPS Oncology & Infusion Center

Fort Worth, United States

Texas Oncology - DFW

Irving, United States

Virginia Cancer Specialists, PC

Fairfax, United States

Virginia Commonwealth University - Massey Cancer Center

Richmond, United States

Northwest Medical Specialties

Tacoma, United States

West Virginia University Hospitals Inc

Morgantown, United States

Aurora BayCare Medical Center

Green Bay, United States

Aurora St Lukes Medical Center

Milwaukee, United States

Centro de Investigaciones Médicas y Desarrollo LC S.R.L

Buenos Aires, Argentina

Inst. de Oncologia Angel H. Roffo

Buenos Aires, Argentina

Centro Oncologico Korben

Ciudad Autonoma Buenos Aires, Argentina

Sanatorio Allende

Córdoba, Argentina

Centro Oncologico Riojano Integral (CORI)

La Rioja, Argentina

Hospital Alemán

Recoleta, Argentina

Instituto de Oncología de Rosario

Rosario, Argentina

Sanatorio Parque S.A.

Rosario, Argentina

Hospital Provincial del Centenario

Rosario, Argentina

Centro Oncológico de Excelencia

San Juan, Argentina

Northern Beaches Hospital

Frenchs Forest, Australia

Nepean Hospital

Kingswood, Australia

Mater Hospital

North Sydney, Australia

University of the Sunshine Coast

Sippy Downs, Australia

Mater Misericordiae Limited

South Brisbane, Australia

Cancer Research SA

Adelaide, Australia

Barwon Health

Geelong, Australia

Sunshine Hospital

St Albans, Australia

South West Healthcare

Warrnambool, Australia

Lkh-Univ. Klinikum Graz

Graz, Austria

Medical University Innsbruck

Innsbruck, Austria

Ordensklinikum Linz Barmherzige Schwestern

Linz, Austria

Oö. Gesundheits- und Spitals-AG/LKH Steyr

Steyr, Austria

Medizinische Universität Wien

Vienna, Austria

Cliniques Universitaires St-Luc

Brussels, Belgium

GHdC Site Les Viviers

Charleroi, Belgium

UZ Gent

Ghent, Belgium

UZ Leuven Gasthuisberg

Leuven, Belgium

CHU de Liège (Sart Tilman)

Liège, Belgium

AZ St Maarten Campus Leopoldstr

Mechelen, Belgium

Clinique Ste-Elisabeth

Namur, Belgium

ZAS Sint Augustinus Wilrijk

Wilrijk, Belgium

Crio - Centro Regional Integrado de Oncologia

Fortaleza, Brazil

CEDOES - Diagnóstico e Pesquisa

Vitória, Brazil

Obras Sociais Irma Dulce - Osid

Salvador, Brazil

Hospital Sírio-Libanês

Brasília, Brazil

Hospital Araujo Jorge

Goiânia, Brazil

Hospital Sao Domingos

São Luís, Brazil

Hospital do Câncer de Londrina

Londrina, Brazil

Hospital do Cancer de Pernambuco - HCP

Recife, Brazil

Vencer Oncoclínica - Centro de Pesquisa do Piauí

Teresina, Brazil

Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda

Ijuí, Brazil

Santa Casa de Misericordia de Porto Alegre

Porto Alegre, Brazil

Hospital Moinhos de Vento

Porto Alegre, Brazil

Hospital Sao Lucas - PUCRS

Porto Alegre, Brazil

Hospital Nossa Senhora da Conceicao

Porto Alegre, Brazil

Hospital de Cancer de Barretos

Barretos, Brazil

Hospital Amaral Carvalho

Jaú, Brazil

Hospital Sírio-Libanês

São Paulo, Brazil

Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda

São Paulo, Brazil

Hospital A. C. Camargo

São Paulo, Brazil

Instituto D'Or de Pesquisa e Ensino

Rio de Janeiro, Brazil

Cross Cancer Institute

Edmonton, Canada

Royal Victoria Regional Health Centre

Barrie, Canada

Credit Valley Hospital/Carlo Fidani Peel Regional Cancer Centre

Mississauga, Canada

Lakeridge Health Oshawa

Oshawa, Canada

Thunder Bay Regional Health Sciences Centre

Thunder Bay, Canada

North York General Hospital

Toronto, Canada

Princess Margaret Cancer Center

Toronto, Canada

CIUSSS du Saguenay Lac-Saint-Jean, Chicoutimi Hospital

Chicoutimi, Canada

CISSS Chaudière-Appalaches

Lévis, Canada

Centre Hospitalier de l'Universite de Montreal (CHUM)

Montreal, Canada

McGill University Health Centre - Glen Site

Montreal, Canada

CHU de Québec - Hôpital du Saint-Sacrement

Québec, Canada

Hopital regional de saint jerome

Saint-Jérôme, Canada

Centre hospitalier regional de Trois-Rivieres

Trois-Rivières, Canada

Allan Blair Cancer Centre

Regina, Canada

Saskatoon Cancer Centre

Saskatoon, Canada

Hospital las Higueras

Concepción, Chile

Medicina de Precisión - Celerity

Las Condes, Chile

Clínica Puerto Montt

Port Montt, Chile

Oncovida

Providencia, Chile

Centro De Cancer Universidad Catolica

Santiago, Chile

Instituto Nacional del Cancer

Santiago, Chile

Icegclinic

Santiago, Chile

Beijing Cancer Hospital

Beijing, China

the First Hospital of Jilin University

Changchun, China

Hunan Cancer Hospital

Changsha, China

West China Hospital of Sichuan University

Chengdu, China

Sichuan Provincial People's Hospital

Chengdu, China

The First Affiliated Hospital, Chongqing Medical University

Chongqing, China

Fujian Medical University Union Hospital

Fuzhou, China

No. 900 Hospital (Fuzhou General Hospital)

Fuzhou, China

Cancer Center, Sun Yat-sen University of Medical Sciences

Guangzhou, China

The Second Affiliated Hospital of Zhejiang University College

Hangzhou, China

Harbin Medical University Cancer Hospital

Harbin, China

Jinan Central Hospital

Jinan, China

Shandong Cancer Hospital

Jinan, China

The First People's Hospital of Yunnan Province

Kunming, China

The First Affiliated Hospital to Henan University of Science and Technology

Luoyang, China

Guangxi Cancer Hospital of Guangxi Medical University

Nanning, China

Zhongshan Hospital Fudan University

Shanghai, China

Fudan University Shanghai Cancer Center

Shanghai, China

Shanxi Province Cancer Hospital

Taiyuan, China

Taizhou Hospital of Zhejiang Province

Taizhou, China

Tianjin Cancer Hospital

Tianjin, China

The Tumor Hospital of Xinjiang Medical University

Ürümqi, China

Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, China

Hubei Cancer Hospital

Wuhan, China

The Second Affiliated Hospital of Xi'an Jiao Tong University

Xi'an, China

Xi'an International Medical Center Hospital

Xi'an, China

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, China

Zhejiang Cancer Hospital

Zhejiang, China

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, China

Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo

Bogota, D.C., Colombia

Clinica Colsanitas S.A. sede Clinica Universitaria Colombia

Bogotá D.C., Colombia

IPS Salud SURA Chipichape Cali

Cali, Colombia

Oncomedica S.A.

Montería, Colombia

Sociedad de Oncología y hematología del Cesar Ltda

Valledupar, Colombia

Clinica CIMCA

San José, Costa Rica

ICIMED Instituto de Investigación en Ciencias Médicas

San José, Costa Rica

Proclinical Pharma

San José, Costa Rica

Kuopio Uni Hospital

Kuopio, Finland

Tampere University Hospital

Tampere, Finland

ICO Paul Papin

Angers, France

Institut Sainte Catherine

Avignon, France

Hopital Jean Minjoz

Besançon, France

Centre Francois Baclesse

Caen, France

Centre Jean Perrin

Clermont-Ferrand, France

Centre Hospitalier Saint Louis

La Rochelle, France

Centre Oscar Lambret

Lille, France

Centre Leon Berard

Lyon, France

Centre Cancerologie Grand Montpellier

Montpellier, France

Institut Jean Godinot

Reims, France

Centre Eugene Marquis

Rennes, France

IUCT Oncopole

Toulouse, France

Gustave Roussy

Villejuif, France

Sozialstiftung Bamberg, Klinikum am Bruderwald, Gynäkologie

Bamberg, Germany

St. Elisabeth Krankenhaus Köln GmbH

Cologne, Germany

DONAU ISAR Klinikum Deggendorf

Deggendorf, Germany

Gynonco Düsseldorf, MVZ Medical Center GmbH

Düsseldorf, Germany

Universitätsklinikum Erlangen

Erlangen, Germany

Kliniken Essen-Mitte

Essen, Germany

Praxis für Interdisziplinäre Onkologie und Hämatologie GbR

Freiburg im Breisgau, Germany

Nationales Centrum für Tumorerkrankungen (NCT)

Heidelberg, Germany

Universitätsklinikum des Saarlandes

Homburg/Saar, Germany

Brustzentrum Rhein-Ruhr Servicegesellschaft mbH

Mönchengladbach, Germany

Rotkreuzklinikum München

München, Germany

Anticancer Hospital Ag. Savas

Athens, Greece

Aretaieio Hospital of Athens

Athens, Greece

University Hospital of Larissa

Larissa, Greece

University Hospital of Patras Medical Oncology

Pátrai, Greece

European Interbalkan Medical Center

Thessaloniki, Greece

Oncomedica

Guatemala City, Guatemala

Celan S.A.

Guatemala City, Guatemala

INTEGRA Cancer Institute

Guatemala City, Guatemala

Onco Go, S.A.

Guatemala City, Guatemala

Grupo Angeles

Guatemala City, Guatemala

Medi-k

Guatemala City, Guatemala

Centro Medico Integral de Cancerologia CEMIC

Salcajá, Guatemala

Pamela Youde Nethersole Eastern Hospital

Hong Kong, Hong Kong

Queen Mary Hospital

Hong Kong, Hong Kong

Orszagos Onkologiai Intezet

Budapest, Hungary

Bács-Kiskun Vármegyei Oktatókórház

Kecskemét, Hungary

B-A-Z Vármegyei Központi Kórház és Egyetemi Oktatókórház

Miskolc, Hungary

Nograd Varmegyei Szent Lazar Korhaz

Salgótarján, Hungary

HealthCare Global Enterprises Limited

Banglore, India

MVR Cancer Centre and Research Institute

Kozhikode, India

Regional Cancer Centre

Trivandrum, India

Sir H. N. Reliance Foundation Hospital and Research Centre

Mumbai, India

Grant Medical Foundation, Ruby Hall Clinic

Pune, India

Sahyadri Speciality Hospital

Pune, India

Sunact Cancer Institute

Thane, India

Max Super Speciality Hospital

New Delhi, India

Hadassah Ein Karem Hospital

Jerusalem, Israel

Rabin Medical Center

Petah Tikva, Israel

Sheba MC

Ramat Gan, Israel

Sourasky Medical Center

Tel Aviv, Israel

Presidio Ospedaliero di Summa-Perrino

Brindisi, Italy

Azienda Ospedaliera di Rilievo Nazionale e di Alta Specialita San Giuseppe Moscati

Avellino, Italy

Azienda Ospedaliera Universitaria Federico II

Naples, Italy

Istituto Nazionale Tumori Irccs Fondazione g. PASCALE

Naples, Italy

Policlinico S.Orsola-Malpighi

Bologna, Italy

I.R.S.T Srl IRCCS

Meldola, Italy

A.O. Universitaria Di Parma

Parma, Italy

RCCS - Centro di Riferimento

Aviano (PN), Italy

A.O. Universitaria S. Maria Della Misericordia Di Udine

Udine, Italy

Policlinico Universitario Agostino Gemelli

Rome, Italy

Università Campus Bio-Medico di Roma

Rome, Italy

Asst Papa Giovanni XXIII

Bergamo, Italy

Asst Degli Spedali Civili Di Brescia

Brescia, Italy

Asst Di Cremona

Cremona, Italy

Irccs Istituto Nazionale Dei Tumori (Int)

Milan, Italy

Istituto Clinico Humanitas

Rozzano, Italy

A.O.U. Maggiore della Carità

Novara, Italy

Humanitas Centro Catanese Di Oncologia

Misterbianco (CT), Italy

Ospedale Di Macerata

Province of Macerata, Italy

Azienda Ospedaliera Universitaria Careggi

Florence, Italy

IOV - Istituto Oncologico Veneto - IRCCS

Padova, Italy

University of Nairobi - Institute of Tropical and Infectious Diseases

Nairobi, Kenya

Panamerican Clinical Research S.A de C.V.

Guadalajara, Mexico

RENATI INNOVATION S.A.P.I. de C.V

Guadalajara, Mexico

Productos y Servicios Oncologicos Acacias SA de CV

Mexico City, Mexico

Centro de Atencion Oncologica Viva S de RL de CV

Mexico City, Mexico

Hospital Zambrano Hellion TecSalud

Monterrey, Mexico

Centro de Investigacion Clinica de Oaxaca

Oaxaca City, Mexico

PanAmerican Clinical Research, Querétaro

Queréaro, Mexico

CENEIT Oncologicos

Mexico City, Mexico

Clinica Alivia sucursal Coyoacan

Mexico City, Mexico

Christchurch Hospital

Christchurch, New Zealand

Palmerston North Hospital

Palmerston North, New Zealand

Whangarei Hospital

Whangarei, New Zealand

Centro Medico Monte Carmelo

Arequipa, Peru

Hospital Goyeneche

Arequipa, Peru

Clínica Santa Beatriz

Lima, Peru

Hospital Nacional Arzobispo Loayza

Lima, Peru

Oncosalud Sac

Lima, Peru

Instituto Nacional de Enfermedades Neoplasicas

Lima, Peru

Clinica Internacional, Sede San Borja

Lima, Peru

Instituto Peruano de Oncología y Radioterapia

Lima, Peru

Clinica San Antonio;Investigaciones Trujillo S.A.C.

Trujillo, Peru

Clinica Peruana Americana

Trujillo, Peru

Instituto Regional de Enfermedades Neoplasicas - IREN Norte

Trujillo, Peru

Instytut "Centrum Zdrowia Matki Polki"

?ód?, Poland

Centrum Onkologii im. Prof. Franciszka ?ukaszczyka

Bydgoszcz, Poland

Szpital Morski Im. Pck

Gdynia, Poland

Narodowy Instytut Onkologii Odzia? w Gliwicach

Gliwice, Poland

?wi?tokrzyskie Centrum Onkologii

Kielce, Poland

Przychodnia Lekarska KOMED, Roman Karaszewski

Konin, Poland

Szpital Wojewódzki im. Miko?aja Kopernika

Koszalin, Poland

Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli

Lublin, Poland

Opolskie Centrum Onkologii

Opole, Poland

Mazowiecki Szpital Wojewódzki im. ?w. Jana Paw?a II

Siedlce, Poland

Zachodniopomorskie Centrum Onkologii

Szczecin, Poland

Narodowy Inst.Onkologii im.Sklodowskiej-Curie Panstw.Inst.Bad

Warsaw, Poland

IPO de Coimbra

Coimbra, Portugal

Hospital de S. Francisco Xavier

Lisbon, Portugal

Hospital da Luz

Lisbon, Portugal

IPO do Porto

Porto, Portugal

CHVNG/E_Unidade 1

Vila Nova de Gaia, Portugal

PanOncology Trials

San Juan, Puerto Rico

Spitalul Clinic Filantropia

Bucharest, Romania

Institutul Oncologic Prof. Dr. Alexandru Trestioreanu

Bucharest, Romania

Amethyst Cluj

Cluj County, Romania

Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj Napoca

Cluj-Napoca, Romania

Centrul de Oncologie Sfantul Nectarie

Craiova, Romania

Institutul Regional de Oncologie Iasi

Iași, Romania

Centrul de Oncologie Oncohelp

Timișoara, Romania

National University Hospital

Singapore, Singapore

National Cancer Centre

Singapore, Singapore

Icon Cancer Centre Gleneagles

Singapore, Singapore

Institute of Oncology Ljubljana

Ljubljana, Slovenia

Cancercare Rondebosch Oncology

Cape Town, South Africa

Cancercare

Port Elizabeth, South Africa

Steve Biko Academic Hospital

Pretoria, South Africa

Wits Clinical Research

Soweto, South Africa

Kyungpook National University Chilgok Hospital

Daegu, South Korea

Seoul National University Bundang Hospital

Seongnam-si, South Korea

Korea University Anam Hospital

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Severance Hospital, Yonsei University Health System

Seoul, South Korea

Asan Medical Center

Seoul, South Korea

Gangnam Severance Hospital

Seoul, South Korea

Ewha Womans University Mokdong Hospital

Seoul, South Korea

Samsung Medical Center

Seoul, South Korea

Ulsan University Hosiptal

Ulsan, South Korea

Institut Catala d?Oncologia Hospital Germans Trias i Pujol

Badalona, Spain

Hospital de Jerez de la Frontera

Jerez de la Frontera, Spain

Hospital Quiron de Madrid

Pozuelo de Alarcón, Spain

Hospital Universitario Virgen de La Arrixaca

EL Palmar (EL Palmar), Spain

Hospital Alvaro Cunqueiro

Vigo, Spain

Hospital Universitari Dexeus - Grupo Quironsalud

Barcelona, Spain

Hospital Universitari Vall d'Hebron

Barcelona, Spain

Hospital Juan Ramon Jimenez

Huelva, Spain

Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico

Jaén, Spain

Centro Oncologico MD Anderson Internacional

Madrid, Spain

Hospital de Madrid Norte Sanchinarro- Centro Integral Oncologico Clara Campal

Madrid, Spain

Hospital Universitario Virgen Macarena

Seville, Spain

Hospital Universitario Virgen del Rocio

Seville, Spain

Instituto Valenciano Oncologia

Valencia, Spain

Hospital Arnau de Vilanova (Valencia) Servicio de Oncologia

Valencia, Spain

Hsin-Chu Branch of National Taiwan University Hospital

Hsinchu, Taiwan

China Medical University Hospital

Taichung, Taiwan

Veterans General Hospital

Taipei, Taiwan

National Taiwan Uni Hospital

Taipei, Taiwan

Koo Foundation Sun Yat-Sen Cancer Center

Taipei, Taiwan

Veterans General Hospital - Taichung

Xitun Dist., Taiwan

Chulalongkorn Hospital

Bangkok, Thailand

National Cancer Institute

Bangkok, Thailand

Rajavithi Hospital

Bangkok, Thailand

Chulabhorn Hospital

Lak Si, Thailand

Maharaj Nakorn Chiang Mai Hospital;Depart of Radiology

Muang Chiang MAI Delivery Branch 3, Thailand

Songklanagarind Hospital

Songkhla, Thailand

Sakarya Training and Research Hospital

Adapazarı, Turkey (Türkiye)

Ankara City Hospital

Ankara, Turkey (Türkiye)

Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji

Bakirkoy / Istanbul, Turkey (Türkiye)

Izmir Ataturk Training and Research Hospital

Izmir, Turkey (Türkiye)

Goztepe Prof.Dr. Suleyman Yalcin City Hospital

Kadiköy, Turkey (Türkiye)

Mersin City Education and Research Hospital

Mersin, Turkey (Türkiye)

Medikal Park Samsun

Samsun, Turkey (Türkiye)

Hacettepe Uni Medical Faculty Hospital

Sihhiye/Ankara, Turkey (Türkiye)