Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This is a phase III, randomized, double-blind, placebo-controlled, multi-center, global study to explore the efficacy and safety of volrustomig in women with high-risk LACC (FIGO 2018 stage IIIA to IVA cervical cancer) who have not progressed following platinum-based CCRT.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Kobiety.
- •Wiek co najmniej 15 lat.
- •Waga ciała powyżej 35 kg.
- •Zdiagnozowany rak szyjki macicy (niektóre typy), który nie rozprzestrzenił się.
- •Stan ogólny pozwalający na udział w badaniu.
- •Dobra praca narządów i szpiku kostnego.
- •Zgoda na udział w badaniu.
✗ Disqualifies
- •Inny typ raka szyjki macicy (np. drobnokomórkowy).
- •Rak, który się rozprzestrzenił.
- •Chęć stosowania leczenia, które chroni płodność.
- •Przeszczep narządu lub komórek macierzystych.
- •Problemy z układem odpornościowym lub choroby autoimmunologiczne.
- •Niekontrolowana choroba współistniejąca.
- •Inne nowotwory w przeszłości (z pewnymi wyjątkami).
- •Nieustępujące powikłania po poprzednim leczeniu (z pewnymi wyjątkami).
Simplified criteria — AI translation
Trial details
- Minimum age
- 15 Years
- Last updated (source)
- July 29, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (205)
Research Site
Birmingham, United States
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Phoenix, United States
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Tucson, United States
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Little Rock, United States
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La Jolla, United States
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West Hollywood, United States
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Atlanta, United States
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Augusta, United States
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Savannah, United States
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Melrose Park, United States
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Indianapolis, United States
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New Orleans, United States
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New Orleans, United States
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Shreveport, United States
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New York, United States
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Syracuse, United States
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Cleveland, United States
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Columbus, United States
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Eugene, United States
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Philadelphia, United States
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Providence, United States
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Dallas, United States
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Fort Worth, United States
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Houston, United States
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Tyler, United States
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Charlottesville, United States
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Fairfax, United States
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Richmond, United States
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Barretos, Brazil
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Belo Horizonte, Brazil
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Curitiba, Brazil
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Fortaleza, Brazil
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Fortaleza, Brazil
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Goiânia, Brazil
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Ijuí, Brazil
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Natal, Brazil
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Porto Alegre, Brazil
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Porto Alegre, Brazil
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Porto Alegre, Brazil
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Porto Velho, Brazil
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Recife, Brazil
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Rio de Janeiro, Brazil
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Salvador, Brazil
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São Paulo, Brazil
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São Paulo, Brazil
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São Paulo, Brazil
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Teresina, Brazil
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Hamilton, Canada
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London, Canada
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Toronto, Canada
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Toronto, Canada
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Montreal, Canada
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Montreal, Canada
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Ste-Foy, Canada
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Beijing, China
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Beijing, China
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Beijing, China
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Changde, China
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Changsha, China
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Changsha, China
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Chengdu, China
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Chengdu, China
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Chongqing, China
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Fuzhou, China
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Ganzhou, China
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Guangzhou, China
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Guangzhou, China
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Hangzhou, China
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Harbin, China
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Kunming, China
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Lanzhou, China
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Lanzhou, China
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Linyi, China
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Luzhou, China
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Nanchang, China
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Nanchang, China
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Shandong, China
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Shanghai, China
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Shanghai, China
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Shenyang, China
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Shenzhen, China
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Shenzhen, China
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Tianjin, China
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Wuhan, China
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Wuhan, China
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Xi'an, China
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Yibin, China
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Yinchuan, China
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Zhengzhou, China
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Zhengzhou, China
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Zhuzhou, China
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Aarhus N, Denmark
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København Ø, Denmark
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Odense, Denmark
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Berlin, Germany
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Bonn, Germany
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Hamburg, Germany
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Leipzig, Germany
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Calicut, India
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Jaipur, India
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Lucknow, India
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Madurai, India
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Mohali, India
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Nagpur, India
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Nashik, India
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Nashik, India
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New Delhi, India
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Vadodara, India
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Bari, Italy
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Bologna, Italy
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Catania, Italy
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Florence, Italy
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Lecco, Italy
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Milan, Italy
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Milan, Italy
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Milan, Italy
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Monza, Italy
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Naples, Italy
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Roma, Italy
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Rome, Italy
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Turin, Italy
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Fukuoka, Japan
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Ginowan-shi, Japan
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Hidaka-shi, Japan
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Kagoshima, Japan
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Kōtoku, Japan
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Kurume-shi, Japan
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Maebashi, Japan
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Matsuyama, Japan
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Morioka, Japan
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Nagoya, Japan
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Osaka, Japan
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Sapporo, Japan
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Sapporo, Japan
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Shinjuku-ku, Japan
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Suita-shi, Japan
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Sunto-gun, Japan
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Toon-Shi, Japan
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Coyoacán, Mexico
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Culiacán, Mexico
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Guadalajara, Mexico
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Guadalajra, Mexico
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Mexico City, Mexico
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México, Mexico
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México, Mexico
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Monterrey, Mexico
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Oslo, Norway
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Trondheim, Norway
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Concepción, Peru
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Lima, Peru
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Lima, Peru
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Lima, Peru
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Lima, Peru
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Lima, Peru
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Lima, Peru
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Bialystok, Poland
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Gdansk, Poland
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Gliwice, Poland
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Krakow, Poland
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Lodz, Poland
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Poznan, Poland
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Warsaw, Poland
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Wroclaw, Poland
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San Juan, Puerto Rico
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Daegu, South Korea
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Goyang-si, South Korea
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Gyeonggi-do, South Korea
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Seoul, South Korea
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Seoul, South Korea
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Seoul, South Korea
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Seoul, South Korea
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A Coruña, Spain
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Barcelona, Spain
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Barcelona, Spain
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Córdoba, Spain
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Girona, Spain
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Hospitalet deLlobregat, Spain
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Madrid, Spain
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Madrid, Spain
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Madrid, Spain
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Madrid, Spain
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Palma de Mallorca, Spain
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Valencia, Spain
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Valencia, Spain
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Changhua, Taiwan
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Kaohsiung City, Taiwan
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Kaohsiung City, Taiwan
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New Taipei City, Taiwan
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Taichung, Taiwan
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Taichung, Taiwan
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Tainan, Taiwan
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Taipei, Taiwan
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Taipei, Taiwan
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Taoyuan, Taiwan
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Bangkok, Thailand
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Bangkok, Thailand
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Bangkok, Thailand
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Muang, Thailand
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Udon Thani, Thailand
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Adana, Turkey (Türkiye)
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Ankara, Turkey (Türkiye)
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Ankara, Turkey (Türkiye)
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Cordaleo, Turkey (Türkiye)
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Istanbul, Turkey (Türkiye)
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Istanbul, Turkey (Türkiye)
Trial contact
AstraZeneca Clinical Study Information Center
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/31/2026.
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