A Study of TQB2102 for Injection in Patients With Recurrent/Metastatic Breast Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

This trial is no longer recruiting — here are similar active trials

Matched by cancer type/biomarker, currently recruiting.

RecruitingPhase III🇵🇱 PolandGastric cancerMetastatic / advanced

The goal of this randomized, double-blind, multi-regional phase 3 study of cadonilimab combined with chemotherapy versus chemotherapy in combination with or without nivolumab for the first-line treatment of participants with HER2-negative, previously untreated, unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma trial is to compare OS between cadonilimab combined with chemotherapy and chemotherapy in combination with or without nivolumab in the ITT population.

RecruitingUnknown phase🇵🇱 PolandColorectal cancerMetastatic / advanced

Metastatic colorectal cancer or mCRC is a cancer that starts in the parts of the large intestine (the colon or rectum) and has already spread to other parts of the body. This cancer can be hard to treat because it can behave differently from one person to another. Over time, treatments may stop working, and side effects can build up. In later treatment stages, there are only a few standard medicine options available. Because of this, studies often look at both how long people live and how treatment affects quality of life. The main aim of this study is to see how long adults in Poland with mCRC live without their cancer getting worse (progression-free survival or PFS) when they receive fruquintinib after at least two previous treatments. Fruquintinib (TAK 113) is a medicine taken by mouth that is designed to slow tumor growth. Other aim is to find out how long adults in Poland with mCRC live while being treated with fruquintinib (overall survival or OS). The study also wants to record how fruquintinib is used in routine care in adults with mCRC in Poland (for example when treatment starts, changes in doses, and how long treatment continues). Another aim is to learn about people with mCRC, such as their medical history and past treatment as well as their quality of life while they are in the study. The study will look at data already existing in the participants' medical charts.

The goal of this clinical trial is to determine the most effective dose of EIK1005 that a person can take safely. Additionally, this study will test how well EIK1005 is tolerated alone and in combination with pembrolizumab in treating patients with advanced cancer.

RecruitingPhase II🇵🇱 PolandLung cancerMetastatic / advanced

The purpose of this study is to evaluate the safety and efficacy of Navlimetostat (BMS-986504) monotherapy or in combination with Izalontamab Brengitecan in participants with advanced or metastatic Non-small Cell Lung Cancer (NSCLC) with homozygous MTAP deletion or MTAP loss after progression on prior therapies.

About the trial

TQB2102 is an antibody-drug conjugate comprised of a humanised antibody against Human Epidermal Growth Factor Receptor 2 (HER2), an enzyme-cleavable linker, and a topoisomerase I inhibitor payload, which combine the ability of antibodies to specifically target tumour cells with the highly potent killing activity of drugs with payloads too toxic for systemic administration. This is a Phase 1/Phase 2 study to evaluate the effectiveness, safety, pharmacokinetics (PK) and anti-drug antibody (ADA) of TQB2102 for injection in subjects with HER2-expressing relapsed/metastatic breast cancer.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Pacjent świadomie zgadza się na udział i podpisuje formularz zgody.
  • •Wiek od 18 do 75 lat.
  • •Rak piersi z obecnością cechy HER2, który powrócił lub dał przerzuty.
  • •Stan ogólny pozwalający na udział w badaniu (punktacja ECOG 0-1).
  • •Szacowany czas przeżycia co najmniej 3 miesiące.
  • •Choroba postępująca lub nietolerancja poprzedniego leczenia.
  • •Główne narządy pracują prawidłowo.
  • •Kobiety w wieku rozrodczym i mężczyźni muszą stosować skuteczną antykoncepcję podczas badania i 6 miesięcy po jego zakończeniu.

✗ Disqualifies

  • •Inny nowotwór zdiagnozowany lub leczony w ciągu ostatnich 3 lat.
  • •Nieustępujące poważne skutki uboczne poprzedniego leczenia (poza wypadaniem włosów).
  • •Duża operacja, biopsja nacięciowa lub poważny uraz w ciągu ostatnich 28 dni.
  • •Nieleczone rany lub złamania.
  • •Przebyta choroba płuc wymagająca leczenia sterydami lub podejrzenie takiej choroby.
  • •Zakrzepica żył lub tętnic.

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
75 Years
Last updated (source)
July 8, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (20)

Anhui Pronvincial Cancer Hospital

Hefei, China

Lu'an People's Hospital

Lu'an, China

Cancer Hospital Chinese Academy of Medical Science

Beijing, China

Chongqing University Cancer Hospital

Chongqing, China

Sun Yat-Sen University Cancer Center

Guangzhou, China

Jiangmen Central Hospital

Jiangmen, China

Guangxi Medical University Cancer Hospital

Nanning, China

Harbin Medical University Cancer Hospital

Harbin, China

Hunan Cancer Hospital

Changsha, China

Ganzhou People's Hospital

Ganzhou, China

Jilin Cancer Hospital

Changchun, China

Liaoning Cancer Hospital & Institute

Shenyang, China

The First Hospital of China Medical University

Shenyang, China

Cancer Hospital Affiliated to Shandong First Medical University

Jinan, China

Linyi Cancer Hospital

Linyi, China

The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine

Xi'an, China

Shanxi Cancer Hospital

Taiyuan, China

Suining Central Hospital

Suining, China

Tianjin Medical University Cancer Institute & Hospital

Tianjin, China

Zhejiang Cancer Hospital

Hangzhou, China

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

You can help another person

We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.