RecruitingPhase IIEN originalGastric cancerHER2 positive

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study to find out whether adding trastuzumab and pembrolizumab to standard chemotherapy is an effective treatment for resectable HER2+ esophagogastric cancer.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Osoby w wieku 18 lat lub starsze.
  • Ogólny stan zdrowia pozwalający na normalną aktywność, z niewielkimi ograniczeniami (status ECOG 0-1).
  • Potwierdzony laboratoryjnie nowotwór przełyku, połączenia przełykowo-żołądkowego lub żołądka z obecnością markera HER2 (HER2-pozytywny).
  • Nowotwór, który można całkowicie usunąć za pomocą operacji.
  • Sprawne narządy wewnętrzne (w tym serce, nerki, wątroba i układ krzepnięcia) – szczegółowe wymagania są podane w dokumentacji badania.

✗ Disqualifies

  • Obecność przerzutów nowotworowych lub nawrót choroby.

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
July 7, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (10)

Massachusetts General Hospital (Data Collection Only)

Boston, United States

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

Basking Ridge, United States

Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

Middletown, United States

Memorial Sloan Kettering Bergen (Limited Protocol Activities)

Montvale, United States

Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity)

Commack, United States

Memorial Sloan Kettering Westchester (Limited Protocol Activities)

Harrison, United States

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, United States

Memorial Sloan Kettering Nassau (Limited Protocol Activities)

Uniondale, United States

University of Pennsylvania (Data Collection Only)

Philadelphia, United States

MD Anderson Cancer Center (Data Collection Only)

Houston, United States

Trial contact

Yelena Janjigian, MD

Samuel Cytryn, MD

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/8/2026.

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