Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that Fenofibrate, a cholesterol-lowering drug, can restore normal function to p53 and can change the metabolism of HPV-positive tumors in a way that stops the growth of tumors. The purpose of this study is to understand how Fenofibrate can be used to treat HPV-positive cervical cancers and cervical dysplasia. Researchers will examine collected tissue samples and investigate various genes and proteins to see whether Fenofibrate has an effect on HPV-positive cervical cancers and cervical dysplasia.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzona badaniem histologicznym lub cytologicznym zmiana wysoko stopniowa lub rak szyjki macicy
- •Kwalifikacja do zabiegu chirurgicznego lub chemioradioterapii
- •Wiek 18 lat lub więcej
- •Prawidłowa funkcja wątroby
- •Umiejętność komunikacji w języku angielskim
- •Zdolność do zrozumienia warunków badania i chęć podpisania zgody
✗ Disqualifies
- •Aktywna choroba wątroby lub problemy z funkcją wątroby
- •Poważne uszkodzenie nerek lub dializa
- •Aktywne kamienie żółciowe lub choroba pęcherzyka żółciowego
- •Uczulenie na fenofibrat
- •Ciąża lub karmienie piersią
- •Potencjalna możliwość zajścia w ciążę - konieczne badanie przed leczeniem
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 27, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (1)
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, United States
Trial contact
Lindsay A Ferguson, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/28/2026.
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