LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This study, known as LUNAR-2, aims to investigate the effectiveness and safety of using TTFields, delivered by the NovoTTF-200T device, concomitantly administered with pembrolizumab and platinum-based chemotherapy for patients with advanced non-small cell lung cancer that has spread to other parts of the body. The primary goals of the study are to assess overall survival and progression-free survival. Secondary objectives include analyzing outcomes based on the specific histology (subtype) of the lung cancer.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek minimum 22 lata (w USA) lub 18 lat (poza USA)
- •Potwierdzony rozległy rak płuc, który rozprzestrzenił się na inne organy
- •Brak poprzedniego leczenia systemowego z powodu raka przerzutowego
- •Ogólny stan zdrowia oceniony jako dobry do prawidłowego
- •Prawidłowe wyniki badań krwi i funkcji narządów
- •Kobiety muszą nie być w ciąży i nie karmić piersią
- •Mężczyźni muszą używać antykoncepcji, jeśli partner jest w wieku rozrodczym
✗ Disqualifies
- •Mieszana postać małokomórkowego i niepłaskokomórkowego raka płuc
- •Obecność konkretnych mutacji genetycznych, dla których dostępna jest specjalistyczna terapia
- •Poprzednia chemioterapia na raka przerzutowego
- •Chirurgia w ciągu ostatnich 3 tygodni
- •Napromienianie płuc powyżej 30 Gy w ostatnich 6 miesiącach
- •Radioterapia w ciągu ostatnich 2 tygodni
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- October 6, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (104)
Central Alabama Research
Birmingham, United States
Western Regional Medical Center, LLC
Goodyear, United States
St. Jude Herritage Medical Group
Fullerton, United States
Hoag Family Cancer Institute - Hoag Memorial Hospital
Newport Beach, United States
Sutter Institute for Medical Research
Sacramento, United States
Baptist MD Anderson Cancer Center, Baptist Health
Jacksonville, United States
Florida Cancer Affiliates - Ocala Oncology
Ocala, United States
Moffitt Cancer Center
Tampa, United States
Northwest Oncology & Hematology
Barrington, United States
Elmhurst Hospital Nancy Knowles Cancer Center
Elmhurst, United States
Edward Cancer Center
Naperville, United States
Cancer Treatment Centers of America (CTCA)
Zion, United States
Parkview Packnett Family Cancer Institute
Fort Wayne, United States
Franciscan Health Indianapolis
Indianapolis, United States
University of Kansas Cancer Center
Westwood, United States
Luminis Health Radiation Oncology - Anne Arundel Health System
Annapolis, United States
University of Kansas Cancer Center - North
Kansas City, United States
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, United States
University of Kansas Cancer Center - Overland Park
Overland, United States
New York Cancer & Blood Specialists (NYCBS)
New Hyde Park, United States
New York Cancer & Blood Specialists (NYCBS)
New York, United States
University of Rochester Medical Center
Rochester, United States
New York Cancer & Blood Specialists (NYCBS)
Shirley, United States
New York Cancer & Blood Specialists (NYCBS)
The Bronx, United States
WakeMed Health & Hospitals
Cary, United States
Abramson Cancer Center
Philadelphia, United States
AHN Cancer Center
Pittsburgh, United States
Old Parkland Hospital Hematology Oncology Clinic
Dallas, United States
UT Southwestern Medical Center
Dallas, United States
DHR Health Oncology Institute
Edinburg, United States
Houston Methodist Cancer Center
Houston, United States
Methodist Richardson Cancer Center
Richardson, United States
Jason Bates at University of Texas Health Science Center
San Antonio, United States
MultiCare Regional Cancer Center
Auburn, United States
MultiCare Regional Cancer Center
Gig Harbor, United States
MultiCare Regional Cancer Center
Puyallup, United States
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
Spokane, United States
MultiCare Institute for Research & Innovation
Tacoma, United States
Universitaetsklinik fuer Innere Medizin V Innsbruck
Innsbruck, Austria
University Hospital Salzburg
Salzburg, Austria
Karl Landsteiner Institut fur Lungenforschung und pneumologische Onkologie c/o Klinik Floridsdorf
Vienna, Austria
Cliniques universitaires Saint-Luc
Brussels, Belgium
AZ Maria Middelares - Campus Maria Middelares
Ghent, Belgium
The Ottawa Hospital Cancer Centre General Campus
Ottawa, Canada
Sunnybrook Health Sciences Center
Toronto, Canada
Fakultni nemocnice Olomouc FNOL
Olomouc, Czechia
Nemocnice Agel Ostrava-Vitkovice / Agel Ostrava-Vitkovice Hospital
Ostrava, Czechia
General University Hospital in Prague
Prague, Czechia
Centre Hospitalier Intercommunal de Creteil
Créteil, France
CHU Limoges
Limoges, France
Hopital Europeen
Marseille, France
Hopital Prive du Confluent
Nantes, France
Institut Curie
Paris, France
CHU de Bordeaux
Pessac, France
Centre Hospitalier Lyon Sud
Pierre-Bénite, France
Nouvel Hopital Civil (NHC)
Strasbourg, France
Evangelische Lungenklinik Berlin
Berlin, Germany
University Hospital Giessen, ZIM IV
Giessen, Germany
Krankenhaus Martha-Maria Halle-Dolau
Halle, Germany
Thoraxklinik Heidelberg
Heidelberg, Germany
Klinik Loewenstein gGmbH
Löwenstein, Germany
Pius-Hospital Oldenburg
Oldenburg, Germany
Farkasgyepui Tudogyogyintezet
Farkasgyepű, Hungary
Bacs-Kiskun Varmegyei Oktatokorhaz
Kecskemét, Hungary
Tolna Varmegyei Balassa Janos Korhaz
Szekszárd, Hungary
Emek Medical Center
Afula, Israel
Bnai zion MC
Haifa, Israel
A.O. SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Alessandria, Italy
Humanitas Gavazzeni
Bergamo, Italy
Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna
Ferrara, Italy
IRCCS - Istituto Romagnolo per lo Studio Dei Tumori, Dino Amadori
Meldola, Italy
Azienda Sanitaria Territoriale Pesaro Urbino
Pesaro, Italy
Universita Campus Bio-Medico di Roma (UCBM) - Policlinico Universitario
Roma, Italy
Ospedale Isola Tiberina Gemelli
Rome, Italy
Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte
Siena, Italy
Kindai University Hospital
Sakai, Japan
Saitama Medical University International Medical Center
Hidaka, Japan
Juntendo University
Bunkyo, Japan
National Cancer Center Hospital
Chuo-ku, Japan
Rijnstate Ziekenhuis
Arnhem, Netherlands
Medisch Centrum Leeuwarden (MCL) - Oncologisch Centrum Leeuwarden (OCL)
Friesland, Netherlands
St. Jansdal ziekenhuis
Harderwijk, Netherlands
St Antonius Ziekenhuis
Utrecht, Netherlands
Uniwersytecki Szpital Kliniczny
Poznan, Poland
NCCS Singapore
Singapore, Singapore
Curie Oncology
Singapore, Singapore
Icon Cancer Centre Singapore (Singapore Oncology Consultants)
Singapore, Singapore
Hospital Universitario del Vinalopo
Elche, Spain
Hospital Universitario Virgen del Rocio
Seville, Spain
Clinica Mi Tres Torres Barcelona - Giromed Institute
Barcelona, Spain
Hospital Universitario de Torrejon
Torrejón de Ardoz, Spain
Institut Catala d'Oncologia
Barcelona, Spain
Hospital Universitario Arnau de Vilanova
Lleida, Spain
Clinica Universidad de Navarra (Madrid)
Madrid, Spain
Hospital Ruber Internacional
Madrid, Spain
Hospital Regional Universitario de Malaga
Málaga, Spain
Clinica Universidad de Navarra
Pamplona, Spain
Cantonal Hospital Baden
Baden, Switzerland
HFR Freiburg-Kantonsspital
Fribourg, Switzerland
Charing Cross Hospital
London, United Kingdom
University Hospitals of Leicester NHS Trust
Leicester, United Kingdom
The Royal Marsden NHS Foundation Trust
London, United Kingdom
Clatterbridge Cancer Centre - Liverpool
Liverpool, United Kingdom
The Royal Marsden NHS Foundation Trust - Sutton
Sutton, United Kingdom
Trial contact
Lorie Szymela
Janiece Denaro
Larissa Ulloa
Patrice Jones
Vanessa Tolsa
John Vu
PRINCIPAL_INVESTIGATOR
Megan Cerrato
Maya Douglas
Khalada Admad
Jessica Schnase
Sylvia Schneiderman
Brian Chang, Dr.
Brian Chang
PRINCIPAL_INVESTIGATOR
Olivia Martin
KUCC Navigation
Rachael Niedelman
Laura Parisi
Sierra Napoli
Taylor Childress
Ariel Lopez-Chavez
Ebele Mbanugo
Edgar Lopez
Nicole Barrios
Jun Zhang
PRINCIPAL_INVESTIGATOR
Crystee Cooper
Epp Goodwin
Stacey Macon
Rachel Smith
Florian Kocher
Richard Greil
Maximilian Hochmair
Rachel Galot
Paul Germonpre
Garth Nicholas
Garth Nicholas
PRINCIPAL_INVESTIGATOR
Vaishali Krishnanandan
Susanna Cheng
PRINCIPAL_INVESTIGATOR
Bohuslav Melichar
Jaromir Roubec
Milada Zemanova
Christos Chouaid
Thomas Egenod
Thomas Egenod
PRINCIPAL_INVESTIGATOR
Remi Bonetto
Cyriac Blonz
Cyriac Blonz
PRINCIPAL_INVESTIGATOR
Nicolas Girard
Claire Bardel
Sebastien Couraud
Celine Mascaux
Norman von-Palubitzki
Anika Holzapfel
Franziska Gebauer
Wolfgang Schuette
PRINCIPAL_INVESTIGATOR
Nicolyn Roessel
Frank Griesinger
Zsolt Kiraly
Zsuzsanna Kelemen
Yousuf Al-Farhat
Gil Bar Sela
Abed Agbarya
Pier Luigi Piovano
Clinical Trial Center
Chiara Catania
Luana Calabro
Angelo Delmonte
Rita Chiari
Giuseppe Tonini
Michele Maio
Hidetoshi Hayashi
Hidetoshi Hayashi
PRINCIPAL_INVESTIGATOR
Saitama Medical University International Medical Center
Takehito Shukuya
Takehito Shukuya
PRINCIPAL_INVESTIGATOR
Hidehito Horinouchi
Hidehito Horinouchi
PRINCIPAL_INVESTIGATOR
Siyar Demir
Johanna Hellinga
Martine Lammens
Lisanne Kastelijn
Rodryg Ramlau
Toh Chee Keong
Daniel Chan
Eugenio Palomares Garcia
Carlos Cabrera
Carlos Cabrera Galvez
Luis Cabezon Gutierrez
Enric Carcereny Costa
Alberto Rodrigo Caceres
Miguel Fernandez de Sanmamed Gutierrez
Antonio Calles Blanco
Airam Padilla Alvarez
Sacha Rothschild
Alessandra Curioni-Fontecedro
Alessandra Curioni-Fontecedro
PRINCIPAL_INVESTIGATOR
Denebeth Calla
Waleed Mohammed
PRINCIPAL_INVESTIGATOR
Clare Belcher
Sean Dulloo
PRINCIPAL_INVESTIGATOR
Michael Davidson
William McCaig
Carles Escriu
PRINCIPAL_INVESTIGATOR
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/7/2026.
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