Analysis of PD-L1, TMB, MSI and ctDNA Dynamics to Predict and Monitor Response to Immunotherapy in Metastatic Cancer.

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is an observational clinical trial, aiming to investigate whether the ctDNA dynamics could predict early response to ICIs in patients with advanced-stage cancer. Moreover, conventional tumor markers PD-L1, TMB and MSI are to be investigated for their combined prognostic values in ICI treatment.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Wiek 18 lat lub więcej, oboje płci
  • Rozpoznany zaawansowany rak (płuc, jelita grubego, piersi, wątroby, żołądka itd.) kwalifikujący się do immunoterapii
  • Dostępna próbka tkanki do badania
  • Zgodność z protokołem leczenia
  • Dobrowolna zgoda pacjenta na udział w badaniu

✗ Disqualifies

  • Pacjent już rozpoczął immunoterapię przed wpisaniem do badania
  • Pacjent już rozpoczął chemioterapię przed wpisaniem do badania
  • Zaburzenia zdrowia psychicznego lub ogólnego mogące utrudniać udział w badaniu
  • Brak zgody pacjenta na udział w badaniu

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
80 Years
Last updated (source)
January 16, 2026
Sex
No restrictions

Locations (2)

University of Medicine and Pharmacy at HCMC

Ho Chi Minh City, Vietnam

Medical Genetics Institute

Ho Chi Minh City, Vietnam

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.

You can help another person

We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.