CtDNA Based MRD Testing for NAC Monitoring in TNBC
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided test to pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in stage I-III triple negative breast cancer (TNBC). Results from this study aim to improve MRD detection and disease outcomes for future patients.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Zdiagnozowany rak piersi potrójnie ujemny.
- •Rak piersi we wczesnym stadium (I-III) i planowane leczenie przedoperacyjne w celu wyleczenia.
- •Pacjentka ma co najmniej 18 lat.
- •Pacjentka rozpoczyna leczenie przedoperacyjne.
- •Zgoda na pobranie próbek krwi przed i w trakcie leczenia.
- •Dostępny materiał z biopsji.
✗ Disqualifies
- •Leczenie innego nowotworu jednocześnie.
- •Rak piersi w stadium IV.
- •Inny nowotwór w ciągu ostatnich 5 lat (z wyjątkiem raka skóry).
- •Przyjmowanie leczenia systemowego raka piersi przed rozpoczęciem badania.
- •Ciąża.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- January 7, 2025
- Sex
- Female only
Locations (14)
Arizona Oncology
Tucson, United States
University of Colorado Cancer Center
Aurora, United States
George Washington University
Washington D.C., United States
Mount Sinai Medical Center of Florida
Miami Beach, United States
Comprehensive Hematology Oncology (ONare Alliance, LLC / Exigent Research, LLC
St. Petersburg, United States
Illinois Cancer Care
Peoria, United States
Louisiana State University
New Orleans, United States
Trinity Health-Michigan
Ypsilanti, United States
Nebraska Methodist
Omaha, United States
Stony Brook University Cancer Center
Stony Brook, United States
Oregon Oncology Specialists
Salem, United States
Cancer Care Associates of York
York, United States
The University of Texas MD Anderson Cancer Center
Houston, United States
Cancer Care Northwest
Spokane, United States
Trial contact
Soumya Chappidi
Julee Hartwell
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/1/2026.
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