Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

Investigators seek to determine the sensitivity and specificity of a combined HPV 16 DNA and host gene methylation oral biomarker panel to distinguish early Oropharyngeal Cancer (OPC) cases from controls among 100 early and 100 late disease pre-treatment OPC cases, and 200 controls matched by sex, age, race/ethnicity, and tobacco use collected from the Moffitt Cancer Center (Moffitt) and the University of Pittsburgh Medical Center Hillman Cancer Center (Pittsburgh).

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek co najmniej 18 lat
  • •Nowo zdiagnozowany rak gardła potwierddzony badaniem histologicznym (wszystkie stopnie zaawansowania)
  • •Brak leczenia (operacja, chemioterapia, radioterapia) w ostatnich czterech tygodniach
  • •Wiek co najmniej 35 lat (dla grupy kontrolnej)
  • •Brak poprzedniego rozpoznania raka gardła lub raka związanego z HPV
  • •Pisemna zgoda na udział w badaniu
  • •Pełne zrozumienie procedur badania

✗ Disqualifies

  • •Niespełnienie kryteriów kwalifikacji dla grupy pacjentów lub kontrolnej

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 23, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (3)

Moffitt Cancer Center

Tampa, United States

University of Nebraska Medical Center

Omaha, United States

University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center

Pittsburgh, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/24/2026.

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