RecruitingPhase IIEN originalLiver cancerMetastatic / advanced

Phase 2 Study of WGI-0301 for Advanced HCC

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to determine the MTD of WGI-0301 in combination with Sorafenib for advanced Hepatocellular Carcinoma (HCC) and assess its safety and efficacy in adults with advanced unresectable HCC who have previously received PD-1 / PD-L1 immune checkpoint inhibitors.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek co najmniej 18 lat
  • •Potwierdzony rozpoznaniem raka wątroby (histologicznie, cytologicznie lub klinicznie)
  • •Zaawansowany rak wątroby niezdatny do operacji i transplantacji
  • •Wcześniejsze leczenie nie przyniosło rezultatu lub pacjent go nie toleruje
  • •Po immunoterapii - potwierdzony postęp choroby lub brak tolerancji leczenia
  • •Ogólny stan zdrowia pozwalający na leczenie (ECOG 0 lub 1)
  • •Co najmniej jeden widoczny guz do zmierzenia na zdjęciach
  • •Zdolność do podjęcia leczenia Sorafenibem

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
September 11, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (9)

China Pharmaceutical University, Shanghai Gobroad Cancer Hospital

Shanghai, China

Hunan Cancer Hospital

Changsha, China

West China Hospital Sichuan University

Chengdu, China

Sir Run Run Shaw Hospital Zhejiang University School of Medicine

Hangzhou, China

Zhejiang Cancer Hospital

Hangzhou, China

Harbin Medical University Cancer Hospital

Harbin, China

Jiangxi Cancer Hospital

Nanchang, China

Tongji Hospital Tongji Medical College of HUST

Wuhan, China

Prince of Wales Hospital

Hong Kong, Hong Kong

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 9/12/2026.

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