RecruitingPhase IIEN originalLeukemiaOther cancers

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

The purpose of this study is to test whether the combination of the drugs called tacrolimus (Tac), methotrexate (MTX) and new dosing strategy of another drug called (rabbit Anti-thymocyte Globulin \[ATG\]) will help prevent the development and/or improve severity of acute and/or chronic GVHD.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek od 18 do 60 lat
  • •Dostępny dawca szpiku - rodzeństwo (pasujące pod względem genetycznym) lub niespokrewniony dawca
  • •Kwalifikacja do intensywnego leczenia przygotowawczego
  • •Prawidłowa funkcja serca (wyrzutność minimum 45%)
  • •Prawidłowa funkcja nerek (przesączanie powyżej 50 mL/minutę)
  • •Prawidłowa funkcja płuc (minimum 50% normy)
  • •Prawidłowa funkcja wątroby (wskaźniki poniżej określonych granic)

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Maximum age
60 Years
Last updated (source)
October 9, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

University of Alabama at Birmingham

Birmingham, United States

Trial contact

Margaret A Thomas, MPH

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/10/2026.

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