Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This phase II trial studies whether different imaging techniques can provide additional and more accurate information than the usual approach for assessing the activity of tumors in patients with newly diagnosed glioblastoma. The usual approach for this currently is magnetic resonance imaging (MRI). This study is trying to learn more about the meaning of changes in MRI scans after treatment, as while the appearance of some of these changes may reflect progressing tumor, some may be due the treatment. Dynamic susceptibility contrast (DSC)-MRIs, along with positron emission tomography (PET) and/or magnetic resonance (MR) spectroscopy, may help doctors tell which changes are a reflection of the treatment and which changes may be due to progressing tumor.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek co najmniej 18 lat
- •Nowo rozpoznany glejak mózgu potwierdzona biopsją
- •Planuje się standardowe leczenie glejaka
- •Wykonane MRI przed operacją i dostępne do przesłania
- •Operacja mózgu wykonana w ciągu ostatnich 7 tygodni
- •MRI po operacji wykonane w ciągu 3 tygodni
- •Brak przeciwwskazań do MRI i gadolinu
- •Brak alergii na substancje kontrastowe używane w badaniach
✗ Disqualifies
- •Ciąża lub karmienie piersią
- •Osoby w wieku rozrodczym muszą mieć ujemny test ciążowy z ostatnich 14 dni
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 18, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (18)
University of Alabama at Birmingham Cancer Center
Birmingham, United States
Cedars-Sinai Medical Center
Los Angeles, United States
Baptist MD Anderson Cancer Center
Jacksonville, United States
Moffitt Cancer Center
Tampa, United States
Emory University Hospital/Winship Cancer Institute
Atlanta, United States
University of Michigan Rogel Cancer Center
Ann Arbor, United States
Carolinas Medical Center/Levine Cancer Institute
Charlotte, United States
Duke University Medical Center
Durham, United States
Wake Forest University Health Sciences
Winston-Salem, United States
Rhode Island Hospital
Providence, United States
Edwards Comprehensive Cancer Center
Huntington, United States
West Virginia University Healthcare
Morgantown, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, United States
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, United States
Froedtert Menomonee Falls Hospital
Menomonee Falls, United States
Medical College of Wisconsin
Milwaukee, United States
Drexel Town Square Health Center
Oak Creek, United States
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, United States
Trial contact
Site Public Contact
Jonathan E. McConathy
PRINCIPAL_INVESTIGATOR
Site Public Contact
Jeremy D. Rudnick
PRINCIPAL_INVESTIGATOR
Site Public Contact
Robert Cavaliere
PRINCIPAL_INVESTIGATOR
Site Public Contact
Joaquim Farinhas
PRINCIPAL_INVESTIGATOR
Site Public Contact
Hui-Kuo G. Shu
PRINCIPAL_INVESTIGATOR
Site Public Contact
Michelle M. Kim
PRINCIPAL_INVESTIGATOR
Site Public Contact
Annick Desjardins
PRINCIPAL_INVESTIGATOR
Site Public Contact
Marc Benayoun
PRINCIPAL_INVESTIGATOR
Site Public Contact
Toni O. Pacioles
PRINCIPAL_INVESTIGATOR
Site Public Contact
Sonikpreet Aulakh
PRINCIPAL_INVESTIGATOR
Site Public Contact
Michael Veronesi
PRINCIPAL_INVESTIGATOR
Site Public Contact
Jennifer M. Connelly
PRINCIPAL_INVESTIGATOR
Site Public Contact
Site Public Contact
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/14/2026.
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