A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
Researchers want to learn if sacituzumab tirumotecan (MK-2870) alone or with other treatments can treat certain gastrointestinal (GI) cancers. The GI cancers being studied are either advanced (the cancer has spread to other parts of the body), or unresectable (the cancer cannot be removed with surgery). The goals of this study are to learn: * About the safety of sacituzumab tirumotecan alone or with other treatments and if people tolerate it * How many people have the cancer respond (get smaller or go away) to treatment
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Pacjent ma jeden z następujących typów raka: jelita grubego, trzustki (gruczolakorak przewodowy), dróg żółciowych.
- •Rak jest zaawansowany (rozsiany) lub nieoperacyjny.
- •Pacjent otrzymał wcześniej leczenie na raka (nie dotyczy wszystkich pacjentów z rakiem dróg żółciowych).
- •Ewentualne skutki uboczne po poprzednich terapiach ustąpiły.
✗ Disqualifies
- •Historia poważnych chorób oczu.
- •Otrzymanie innego leczenia przeciwnowotworowego (w tym badanych leków) w ciągu ostatnich 4 tygodni przed rozpoczęciem badania.
- •Historia lub obecny stan zapalny płuc (zapalenie płuc/choroba śródmiąższowa płuc), który wymagał leczenia sterydami lub nie można go wykluczyć.
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 1, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (55)
UCLA ( Site 0317)
Los Angeles, United States
University of Colorado Anschutz Medical Campus ( Site 0299)
Aurora, United States
University of Colorado Anschutz Medical Campus ( Site 0325)
Aurora, United States
University of Colorado Anschutz Medical Campus ( Site 0326)
Aurora, United States
Sibley Memorial Hospital ( Site 0310)
Washington D.C., United States
University of Florida College of Medicine ( Site 0281)
Gainesville, United States
Mount Sinai Cancer Center ( Site 0287)
Miami Beach, United States
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0303)
Marietta, United States
Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 0327)
Mineola, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 0324)
New York, United States
University of Texas MD Anderson Cancer Center ( Site 0316)
Houston, United States
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 0295)
Roanoke, United States
University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0293)
Madison, United States
Westmead Hospital ( Site 0003)
Westmead, Australia
Royal Brisbane and Women's Hospital-Medical Oncology Clinical Trials Unit, Cancer Care Services ( Site 0001)
Brisbane, Australia
Epworth Freemasons ( Site 0005)
East Melbourne, Australia
Frankston Hospital-Oncology and Haematology ( Site 0004)
Frankston, Australia
One Clinical Research ( Site 0002)
Nedlands, Australia
The Ottawa Hospital Cancer Centre ( Site 0027)
Ottawa, Canada
Centre Hospitalier de l'Université de Montréal-Unit for Innovative Therapies ( Site 0022)
Montreal, Canada
McGill University Health Centre ( Site 0023)
Montreal, Canada
James Lind Centro de Investigacion del Cancer ( Site 0048)
Temuco, Chile
FALP-UIDO ( Site 0041)
Providencia, Chile
Clínica UC San Carlos de Apoquindo ( Site 0043)
Santiago, Chile
Bradfordhill-Clinical Area ( Site 0047)
Santiago, Chile
Beijing Cancer hospital-Digestive Oncology ( Site 0061)
Beijing, China
The 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army ( Site 0063)
Fuzhou, China
Wuhan Union Hospital Cancer Center. ( Site 0064)
Wuhan, China
Hunan Cancer Hospital-intervention department ( Site 0066)
Changsha, China
Renji Hospital Shanghai Jiao Tong University School of Medicine-Oncology Department ( Site 0067)
Shanghai, China
West China Hospital, Sichuan University ( Site 0068)
Chengdu, China
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 0101)
Milan, Italy
ASST Grande Ospedale Metropolitano Niguarda ( Site 0102)
Milan, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 0103)
Roma, Italy
National Cancer Center Hospital East ( Site 0121)
Kashiwa, Japan
Kanagawa Cancer Center ( Site 0122)
Yokohama, Japan
Seoul National University Hospital ( Site 0161)
Seoul, South Korea
Severance Hospital, Yonsei University Health System ( Site 0164)
Seoul, South Korea
Asan Medical Center ( Site 0163)
Seoul, South Korea
Samsung Medical Center ( Site 0162)
Seoul, South Korea
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 0183)
Madrid, Spain
Hospital Universitario Central de Asturias-Medical Oncology ( Site 0182)
Oviedo, Spain
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0181)
Barcelona, Spain
Hôpitaux Universitaires de Genève (HUG) ( Site 0202)
Geneva, Switzerland
Ospedale Regionale Bellinzona e Valli ( Site 0201)
Bellinzona, Switzerland
China Medical University Hospital ( Site 0223)
Taichung, Taiwan
National Cheng Kung University Hospital-Clinical Trial Center ( Site 0224)
Tainan, Taiwan
National Taiwan University Hospital-Oncology ( Site 0225)
Taipei, Taiwan
Taipei Veterans General Hospital ( Site 0221)
Taipei, Taiwan
Chang Gung Medical Foundation-Linkou Branch ( Site 0222)
Taoyuan, Taiwan
Hacettepe Universite Hastaneleri-oncology hospital ( Site 0241)
Ankara, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 0242)
Ankara, Turkey (Türkiye)
Barts Health NHS Trust ( Site 0263)
London, United Kingdom
Royal Free Hospital ( Site 0262)
London, United Kingdom
University Hospital Coventry & Warwickshire ( Site 0266)
Coventry, United Kingdom
Trial contact
Toll Free Number
Contact information from ClinicalTrials.gov. Contact in English.
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/3/2026.