RecruitingPhase IIEN originalHead and neck cancer

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

⚠️

This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

This is a single institution phase II study that will enroll patients with T0-3N0-2 p16-positive oropharyngeal squamous cell carcinoma (OSCC) undergoing resection of all gross visible disease at the primary site and in the lymph nodes.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • Rak płaskonabłonkowy gardła związany z wirusem HPV (potwierdzone badaniami)
  • Guz o rozmiarze T0-3 i zaangażowaniem węzłów chłonnych N0-2
  • Całkowite chirurgiczne usunięcie wszystkich widocznych zmian nowotworowych
  • Wykonana operacja węzłów chłonnych na szyi
  • Obecność co najmniej jednego czynnika ryzyka (duży guz, wiele zajętych węzłów, rozległa inwazja)
  • Dla pacjentów zgłoszonych przed operacją: wykrywalny DNA wirusa HPV w badaniu krwi
  • Wiek co najmniej 18 lat

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
August 5, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (4)

Cedars-Sinai Cancer at Beverly Hills (THO)

Beverly Hills, United States

Cedars Sinai Medical Center

Los Angeles, United States

CS Cancer at Valley Oncology Medical Group

Tarzana, United States

CS Cancer at the Hunt Cancer Center

Torrance, United States

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/6/2026.

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