Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

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This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.

About the trial

GENCONCOR-1 study is translational research aimed to investigate the concordance of the molecular genetic profile of the primary tumor and brain metastases (BM) of colorectal cancer (CRC). The study was conducted by post hoc analysis of pairs of samples of histological material with determination of the mutational status of genes KRAS, NRAS, BRAF, HER2 and MSI.

Original English text from ClinicalTrials.gov

Who can (and can't) join

✓ Qualifies

  • •Wiek powyżej 18 lat
  • •Potwierdzony histologicznie rak jelita grubego lub odbytnicy
  • •Potwierdzony histologicznie przerzut do mózgu
  • •Przeprowadzona operacja usunięcia przerzutu z mózgu
  • •Dostępne próbki zarówno pierwotnego nowotworu jak i tkanki z mózgu

✗ Disqualifies

  • •Brakuje jednej z dwóch próbek do porównania
  • •Niewystarczająca jakość próbki lub zbyt mało materiału do badania genetycznego

Simplified criteria — AI translation

Trial details

Minimum age
18 Years
Last updated (source)
October 5, 2026
Sex
No restrictions

Therapies / drugs in trial

Locations (1)

Blokhin's Russian Cancer Research Center

Moscow, Russia

Trial contact

Contact information from ClinicalTrials.gov. Contact in English.

Share this trial

Data from ClinicalTrials.gov. AI-assisted translation, last sync: 10/6/2026.

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