Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The phase II trial evaluates the effectiveness of cryocompression therapy alone or in combination with cilostazol in preventing paclitaxel-induced peripheral neuropathy (numbness, pain or tingling in the feet and hands) for patients with gynecologic cancers. Peripheral neuropathy is a common side effect of many chemotherapeutic agents, including paclitaxel. Paclitaxel is in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Cryocompression is a therapy that combines compression garments or dressings with cooling of the treated area. Cilostazol is in a class of medications called platelet-aggregation inhibitors (antiplatelet medications). It works by improving blood flow to the legs. Giving cilostazol together with cryocompression may be safe and tolerable in treating patients with gynecological cancers.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Wiek 18 lat lub więcej
- •Diagnoza raka macicy, jajnika, jajowodu, otrzewnej, szyjki macicy lub sromu
- •Planowana chemioterapia: 6-9 cykli paclitaxelu z carboplatiną lub cisplatyną
- •Ogólny stan zdrowia pozwalający na uczestnictwo w badaniu
✗ Disqualifies
- •Wcześniejsze leczenie paclitaxelem
- •Już istniejące uszkodzenie nerwów rąk lub nóg wymagające leków
- •Cukrzyca słabo kontrolowana
- •Ciężkie problemy z wątrobą
- •Zespół Raynauda (zaburzenie krążenia w dłoniach i stopach)
- •Otwarte rany na rękach lub stopach
- •Poważne zaburzenia rytmu serca lub choroby serca
- •Alergia na cilostazol
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- August 27, 2026
- Sex
- Female only
Therapies / drugs in trial
Locations (3)
Emory University Hospital Midtown
Atlanta, United States
Emory University Hospital/Winship Cancer Institute
Atlanta, United States
Emory Saint Joseph's Hospital
Atlanta, United States
Trial contact
Susan Modesitt, MD
Sharese Windley
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/28/2026.
You can help another person
We fund the Radar, this site, and the development of our Grosz dla Życia fundraising platform from donations and our own resources. Every contribution, even a small one, really helps.