A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a therapy to induce complete Minimum Residual Disease (MRD) negative response
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony diagnoza białaczki limfoblastycznej z komórek T lub chłoniaka limfoblastycznego
- •Choroba nawrotowa lub odporna na leczenie, lub wykrycie przetrwałych komórek nowotworowych
- •Wiek co najmniej 6 miesięcy
- •Prawidłowe funkcjonowanie narządów wewnętrznych
- •Ogólny stan zdrowia pozwalający na udział w badaniu
✗ Disqualifies
- •Poprzednie leczenie inną terapią skierowaną na CD7
- •Poważna hemolityczna anemia (rozpad czerwonych krwinek)
- •Choroba przeszczepiona przeciwko gospodarzowi stopnia 2-4 wymagająca leczenia immunosupresyjnego
- •Rozległa przewlekła choroba przeszczepiona przeciwko gospodarzowi wymagająca leczenia ogólnoustrojowego
Simplified criteria — AI translation
Trial details
- Minimum age
- 1 Year
- Last updated (source)
- August 6, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (17)
City of Hope
Duarte, United States
Children's Hospital Los Angeles
Los Angeles, United States
Colorado Blood Cancer Institute
Denver, United States
Children's National Hospital
Washington D.C., United States
H. Lee Moffitt Cancer Center and Research Institute Hospital
Tampa, United States
Children's Hospital of Atlanta
Atlanta, United States
Washington University Saint Louis
St Louis, United States
Oncology Hematology Care
Cincinnati, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Children's Hospital of Philadelphia
Philadelphia, United States
TriStar Bone Marrow Transplant / Sarah Cannon Transplant & Cellular Therapy
Nashville, United States
MD Anderson Cancer Center
Houston, United States
Sarah Cannon Transplant and Cellular Therapy Methodist Hospital
San Antonio, United States
Sarah Cannon, Virginia Oncology Associates
Norfolk, United States
Seattle Children's Hospital
Seattle, United States
Peter Mac Callum Cancer Institute
Melbourne, Australia
Royal Children's Melbourne
Melbourne, Australia
Trial contact
Wugen Clinical Trials
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 8/7/2026.
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